Results 101 to 110 of about 14,254,330 (297)

Integrated Synthetic Platforms for Chemical Probes: A Journey through the Routes of Flow Processing

open access: yes, 2017
The talk will focus on our recent efforts directed towards the design and implementation of integrated flow platforms for the production of chemical probes and compound library in drug discovery ...
Gioiello, A.
core  

Digital Slump Flow: Image-based assessment of fresh concrete homogeneity as part of the slump flow test

open access: yesCase Studies in Construction Materials
Worldwide, the standardized flow table test, the slump flow test or likewise methods are applied for the characterization of the workability of fresh concrete.
Tobias Schack, Max Coenen, Michael Haist
doaj   +1 more source

Universal Flow Theory Part III

open access: yes
This volume extends the Universal Flow Theory into quantum mechanics and thermodynamics. It introduces the State Coefficient S as a unifying parameter that links quantum flow, thermal processes, entropy, and particle–wave behavior. The work expands Planck’s relation, Boltzmann’s entropy, heat transfer equations, the Schrödinger formulation, and ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A comprehensive investigation of hydraulic performance and internal flow characteristics of Francis turbine model at part load cavitating flow for various turbulence models

open access: yesEngineering Applications of Computational Fluid Mechanics
Francis turbines are used extensively in hydropower facilities because of their great efficiency and versatility in a wider range of operations. In high specific speed turbines, part-load (PL) operations and cavitating conditions introduce highly complex
Mohammad Abu Shahzer   +2 more
doaj   +1 more source

Modelling of flow in pipes and ultrasonic flowmeter bodies

open access: yesEPJ Web of Conferences, 2014
The contribution gives a summary of the flow modelling in flow parts of ultrasonic flowmeters using CFD system ANSYS/FLUENT. The article describes the basic techniques used to create CFD models of flow parts flow and selected results of the flow fields ...
Matas Richard, Cibera Vaclav, Syka Tomas
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Flow Theory Part VI

open access: yes
Volume VI completes the deep integration of the Universal Flow Theoryacross all scientific scales — from subatomic particles to galaxies.It establishes the four levels of unification: material, dynamic,energetic, and structural, showing that all physical and chemicalphenomena emerge from transitions of flow states described by thecoefficient S (0.1 → 1
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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