Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Numerical Study on the Unstable Flow Dynamics of Wormlike Micellar Solutions past a Sphere in the Creeping Flow Regime. [PDF]
Polymers (Basel), 2023 Su X, Wang Z, Liu J, Wu S.
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Influence of flow regime on the decomposition of diluted methane in a nitrogen rotating gliding arc. [PDF]
Sci Rep, 2022 J A, Rao L.
europepmc +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Floating medium flocculator/filter : is unsaturated flow regime superior to saturated flow regime?
, 1998 Floating medium flocculator/filter : is unsaturated flow regime superior to saturated flow ...
S Vigneswaran (13389216) +5 more
core
Study on Feasibility of the Vortex Tool for Gas Well Fluid Drainage in Different Flow Regimes
Shiyou jixie, 2018 At present, the mechanism research of vortex tools in China mainly uses Fluent software to simulate the flow field, which ignores the actual flow regime distribution in the wellbore and the applicability of the vortex tool in each flow regime, leading to
Shi Yifan, Yan Tingjun, Zhao Xuhe
doaj
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Comparison of the simulated and LIDAR measured atmospheric density and temperature in transitional flow regime [PDF]
, 2014 The understanding of the atmosphere in the transitional flow regime is quite limited,due to the limited accuracy of measurement data.In the proposed paper,the atmospheric density and temperature at around 100 km altitude are analyzed,by using numerical ...
万田 +6 more
core +2 more sources
Science and Technology of Nuclear Installations, 2015 In earlier study we have demonstrated that RELAP5 can predict flow instability parameters (flow rate, oscillation period, temperature, and pressure) in single channel tests in CIRCUS-IV facility. The main goals of this work are to (i) validate RELAP5 and
Viet-Anh Phung, Pavel Kudinov
doaj +1 more source