Results 61 to 70 of about 4,208,553 (288)
Dimensional regimes in Kolmogorov flow
Physical Review FluidsWe study the dimensionality of two-dimensional Kolmogorov flows over a wide range of Reynolds numbers and forcing wavenumbers $k_f=\{2,4,8\}$ using two complementary approaches: convolutional autoencoders and a Kaplan-Yorke estimation based on Lyapunov analysis.
Melisa Y. Vinograd +2 more
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Linking Flow Regime and Water Quality in Rivers: a Challenge to Adaptive Catchment Management
Ecology and Society, 2008 Water quality describes the physicochemical characteristics of the water body. These vary naturally with the weather and with the spatiotemporal variation of the water flow, i.e., the flow regime.
Christer Nilsson +1 more
doaj +1 more source
Hydrodynamic fluctuations in the Kolmogorov flow: Nonlinear regime [PDF]
Physical Review E, 1999 In a previous paper [I. Bena, M. Malek Mansour, and F. Baras, ``Hydrodynamic fluctuations in the Kolmogorov flow: Linear regime", Phys. Rev. E 59, 5503 - 5510 (1999)] the statistical properties of the linearized Kolmogorov flow have been studied, using the formalism of fluctuating hydrodynamics.
Bena, Ioana +2 more
openaire +8 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ecosphere, 2019 Spatiotemporal variability in flow determines the physical structures of habitat. During low flows, aquatic organisms can be exposed to reduced dissolved oxygen concentrations, increased water temperature, and desiccation, whereas at high flows ...
Charles R. Randklev +4 more
doaj +1 more source
Flow regime analysis of non-Newtonian duct flows [PDF]
Physics of Fluids, 2006 Reoriented duct flows of generalized Newtonian fluids are an idealization of non-Newtonian fluid flow in industrial in-line mixers. Based on scaling analysis and computation we find that non-Newtonian duct flows have several limit behaviors, in the sense that such flows can become (nearly) independent of one or more of the rheological and dynamical ...
Speetjens, Michel +2 more
openaire +4 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Effects of irrigation dams on riverine biota in mountain streams
Frontiers in Environmental ScienceMountain streams harbor unique biodiversity and provide essential ecosystem services to human societies. Yet, these ecosystems face numerous threats, such as the construction of dams and land use changes, leading to rapid habitat degradation, water ...
Cássia Rocha Pompeu +2 more
doaj +1 more source