Results 71 to 80 of about 9,521,895 (308)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A General Scaling Law of Vascular Tree: Optimal Principle of Bifurcations in Pulsatile Flow [PDF]

open access: yesJournal of Applied Fluid Mechanics
Murray’s law, as the best-known optimal relationship between bifurcation calibers, is obtained based on the assumption of steady-state Poiseuille blood flow and is mostly accurate in small vessels.
M. Shumal   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Analysis of in situ water velocity distributions in the lowland river floodplain covered by grassland and reed marsh habitats - a case study of the bypass channel of Warta River (Western Poland)

open access: yesJournal of Hydrology and Hydromechanics, 2017
The analysis of in situ measurements of velocity distribution in the floodplain of the lowland river has been carried out. The survey area was located on a bypass channel of the Warta River (West of Poland) which is filled with water only in case of ...
Laks Ireneusz   +2 more
doaj   +1 more source

THE RESISTANCE TO FLOW IN WOOD VESSELS

open access: yesAnnals of Botany, 1905
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Numerical Simulation of New Types Mechanical Filter Structure Used for the Railway Vehicles

open access: yes机车电传动, 2015
Based on the analysis of the usual used GL mechanical filter, three new types of mechanical filters were put forward. The two dimension cyclic symmetric geometry model was built, and combined SIMPLE algorithm with the Realizable k-ε turbulent model and ...
WANG Weibin   +3 more
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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