Results 51 to 60 of about 2,404,496 (308)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hydraulic Resistance of Vegetation in River Flow Applications [PDF]

, 2006
Proceedings of the Seventh International Conference on Hydroscience and Engineering, Philadelphia, PA, September 2006. http://hdl.handle.net/1860/732If vegetated regions become part of a river’s flow field, the hydraulic resistance of vegetation ...
Augustijn, Denie C.M., Hulscher, Susanne J.M.H., Huthoff, Fredrik   +2 more
core   +2 more sources

FLOW RESISTANCE OF STEPPED CHANNEL FLOWS

PROCEEDINGS OF HYDRAULIC ENGINEERING, 2000
Many researchers have investigated the friction factor of stepped channel flows, but general agreement has not been obtained. Because a method for evaluating a supercritical depth of the stepped channel flow might not be established. Further, the hydraulic condition required to form a quasi-uniform flow on the steppedchannel has not been clarified ...
Youichi YASUDA, Masayuki TAKAHASHI, Iwao OHTSU   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Pressure Drop Across Animal Occupied Zone of Dairy Barns Under Multiple Scenarios

Agriculture
In naturally ventilated dairy barns, many questions regarding airflow, indoor air quality, and emissions are still unanswered, often resulting in inaccurate environmental control of the housing.
Qianying Yi, El Hadj Moustapha Doumbia, Ali Alaei, David Janke, Thomas Amon, Sabrina Hempel   +5 more
doaj   +1 more source

Scaling Theory of Conduction Through a Normal-Superconductor Microbridge [PDF]

, 1994
The length dependence is computed of the resistance of a disordered normal-metal wire attached to a superconductor. The scaling of the transmission eigenvalue distribution with length is obtained exactly in the metallic limit, by a transformation onto ...
A. F. Volkov, A. Kastalsky, B. J. van Wees, B. Rejaei, C. Nguyen, C. W. J. Beenakker, C. W. J. Beenakker, F. W. J. Hekking, G. E. Blonder, I. K. Marmorkos, J. A. Melsen, K. Slevin, O. N. Dorokhov, P. A. Mello, P. A. Mello, T. Carleman, W. J. Beenakker, Y. Imry, Y. Takane   +18 more
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Numerical Investigation of Heat Transfer and Flow Resistance of Fluoride Salt on Shell Side of Helically Coiled Heat Exchangers

Energies
The Helically Coiled Heat Exchanger (HCHX) is a promising candidate for modular Molten Salt Reactors (MSRs), valued for its high heat transfer efficiency, structural compactness, reduced fouling tendency, and excellent thermal compensation capabilities ...
Yu Wang, Qi-Ming Li, Yang Zou
doaj   +1 more source

Analysis of Flow Resistance in Trifurcation Fluid Networks [PDF]

Journal of Applied Fluid Mechanics
In branch-like structures, branching parameters such as branching diameter, angle, length and number of levels, as well as branching number, have been important research topics in the field of fluid transport.
M. Mustafaoglu, M. Kaan Yesilyurt, İ. Kotcioglu, M. Allahyari   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source