Results 51 to 60 of about 16,101 (216)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
EnergiesThe disadvantage of phase change materials (PCMs) that store thermal energy is their low thermal conductivity. The macro-, micro-, and nanoencapsulation of PCMs are some of the ways to eliminate this drawback.
Krzysztof Dutkowski, Marcin Kruzel
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Experimental studies on thermal and flow resistance behaviors of turbulent flow through a heat exchanger tube with conical-diffuser inserts [PDF]
Warasan Witthayasat Lae Theknoloyi Mahawitthayalai Mahasarakham, 2019 In this research, an experimental investigation of the thermal and flow friction characteristics of tubular heat exchanger (HE) for single-phase forced convective flow with conical-diffuser inserted in the inner tube was performed.
Sompol Skullong
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Numerical Simulation of High Efficiency Screwed Pipe Structure Optimization
Shiyou jixie, 2018 Most of the papers have focused on the influence of the structural parameters of the one-way screwed pipe on its heat transfer performance and flow resistance. Little res earch has been reported on the cross-screwed pipe.
Ge Yinhai, Liu Guixi, Liu Feng, Ji Lite
doaj
Indirect Acoustic Characterisation of Membranes for the Control of Sound Absorption
BuildingsMembranes can be used in different ways to achieve improvements in sound absorption. They can be used on top of base materials (sound-absorbing materials or other kinds) in such a way that they barely increase the thickness while increasing the sound ...
Jesús Alba +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
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