Results 41 to 50 of about 598,432 (318)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Investigations of Ventilation Airflow Characteristics on a Longwall Face—A Computational Approach

open access: yesEnergies, 2018
Mine ventilation has always been critical for underground mining operations to ensure operational efficiency and compliance with safety and health statutory requirements.
Zhongwei Wang   +3 more
doaj   +1 more source

Viscoelastic phase separation in shear flow [PDF]

open access: yesPhysical Review E, 2004
16pages, 16figures, to be published in Phys.Rev ...
Imaeda, Tatsuhiro   +2 more
openaire   +3 more sources

Parameter study for a slatless 2D high-lift airfoil with active separation control using a URANS approach

open access: yes, 2013
The numerical investigations described in the present paper deal with active flow separation control for a 2D, 2-element high-lift airfoil. Here, the aim of the flow control application is to actively reduce or eliminate a large flow separation on the ...
V. Ciobaca, Ciobaca, Vlad
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The effects of non-normality and nonlinearity of the Navier–Stokes operator on the dynamics of a large laminar separation bubble [PDF]

open access: yes, 2010
Publisher version : http://pof.aip.org/resource/1/phfle6/v22/i1/p014102_s1?isAuthorized=noThe effects of non-normality and nonlinearity of the two-dimensional Navier–Stokes differential operator on the dynamics of a large laminar separation bubble over a
DE PALMA, Pietro   +6 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

NUMERICAL INVESTIGATION OF LIQUID CARRYOVER IN T-JUNCTION WITH DIFFERENT DIAMETER RATIOS

open access: yesPlatform, a Journal of Engineering, 2017
T-junction is commonly used in distributing two-phase flow in a piping system, especially in oil and gas industries. In offshore Malaysia, T-junction is installed at the production header as a compact separator to tap produced gas from reservoir as fuel ...
Ahmed Saieed   +3 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of Nacelle Inlet Geometry on Crosswind Distortion Under Ground Static Conditions

open access: yesAerospace
The aerodynamic performance of nacelle inlets under crosswind conditions is crucial for engine stability and efficiency. Current parametric investigations are predominantly focused on cruise operations, with minimal consideration given to crosswind ...
Xiufeng Song   +3 more
doaj   +1 more source

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