Results 51 to 60 of about 1,839,129 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Viscous effects on the position of cavitation separation from smooth bodies [PDF]

open access: yes, 1975
Flow visualization by the schlieren technique in the neighbourhood of a fully developed cavity on two axisymmetric headforms has shown the existence of laminar boundary-layer separation upstream of cavitation separation, and the distance between the two ...
Arakeri, Vijay H.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Adaptive Separation Control System Using Vortex Generator Jets for Time-Varying Flow

open access: yesJournal of Applied Fluid Mechanics, 2008
Flow separation is mostly an undesirable phenomenon and boundary layer control is an important technique for flow separation problems on airfoils and in diffusers.
H Hasegawa, S Kumagai
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Improving Wind Turbine Power with Boundary Layer Suction [PDF]

open access: yesJournal of Applied Fluid Mechanics
Given the vast global capacity of wind turbines, even minor enhancements in their overall performance can substantially increase energy production. To achieve this, several techniques have been developed and implemented commercially to create advanced ...
S. Sadi, M. R. Asayesh, S. A. Moussavi
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experimental study on Header-orifice Vapor-liquid Separation Unit using Zeotropic Mixture

open access: yesZhileng xuebao
Vapor-liquid separation technology can achieve enhanced heat transfer while reducing pressure drop. Vapor-liquid separation unit is the key to achieve efficient vapor-liquid separation.
CHEN Guanghao   +6 more
doaj   +2 more sources

INFLUENCE OF MEMBRANE AMPLITUDE AND FORCING FREQUENCY ON SYNTHETIC JET VELOCITY

open access: yesTASK Quarterly, 2015
This paper presents the results of numerical investigations of a synthetic jet actuator for an active flow control system. The Moving Deforming-Mesh method as a boundary condition is used to capture the real physical phenomenon.
MARCIN KUROWSKI, PIOTR DOERFFER
doaj   +1 more source

Dynamic flow distortion investigation in an S-duct using DDES and SPIV data [PDF]

open access: yes, 2016
The dynamic flow distortion generated within convoluted aero-engine intakes can affect the performance and operability of the engine. There is a need for a better understanding of the main flow mechanisms which promote flow distortion at the exit of S ...
Chiereghin, Nicola   +5 more
core   +1 more source

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