Results 41 to 50 of about 161,061 (357)
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Robust multi-objective hybrid flow shop scheduling
Journal of Applied Research on Industrial Engineering, 2021 Scheduling is an important decision-making process that aims to allocate limited resources to the jobs in a production process. Among scheduling problems, Hybrid Flow Shop (HFS) scheduling has good adaptability with most real world applications including
Behnaz Zanjani +3 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
IEEE Access, 2021 Flow Shop Scheduling Problem (FSSP) has significant application in the industry, and therefore it has been extensively addressed in the literature using different optimization techniques.
B. Khurshid +5 more
semanticscholar +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
A novel hybrid genetic algorithm to solve the make-to-order sequence-dependent flow-shop scheduling problem [PDF]
, 2014 Flow-shop scheduling problem (FSP) deals with the scheduling of a set of n jobs that visit a set of m machines in the same order. As the FSP is NP-hard, there is no efficient algorithm to reach the optimal solution of the problem. To minimize the holding,
Ghomi, S.M.T. Fatemi +2 more
core +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Journal of Industrial Engineering International, 2017 Flexible flow shop (or a hybrid flow shop) scheduling problem is an extension of classical flow shop scheduling problem. In a simple flow shop configuration, a job having ‘g’ operations is performed on ‘g’ operation centres (stages) with each stage ...
Raviteja Buddala, Siba Sankar Mahapatra
doaj +1 more source
Selected heuristic algorithms for solving job shop and flow shop scheduling problems [PDF]
, 2014 Importance of job shop and flow shop scheduling has increased to a high extent. Nowadays, each and every industry focuses largely on how to schedule their machine working, since it is an important factor which decides the net productivity.
Das, M K
core
Flexible flow shop scheduling with stochastic processing times: A decomposition-based approach [PDF]
, 2012 Flexible flow shop scheduling problems are NP-hard and tend to become more complex when stochastic uncertainties are taken into consideration. Although some methods have been developed to address such problems, they remain inherently difficult to solve ...
Choi, SH, Wang, K
core +1 more source