Results 51 to 60 of about 84,491 (259)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Resource Speed Optimization for Two-Stage Flow-Shop Scheduling [PDF]
, 2015 Multiple resource co-scheduling algorithms and pipelined execution models are becoming increasingly popular, as they better capture the heterogeneous nature of modern architectures.
Alessandra Melani +4 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Sequencing CONWIP flow-shops: Analysis and heuristics [PDF]
In this paper, we address the backlog sequencing problem in a flow-shop controlled by a CON\VIP production control system with the objective to minimise the make span We characterise the problem and analyse its similarities and differences with the ...
Framiúnan, Jose M. +2 more
core
Scheduling of Flexible Manufacturing Systems using Intelligent heuristic search algorithm (IHSA*) [PDF]
, 2012 The complete scheduling of FMS includes two independent processes: sequencing of jobs and scheduling those prioritized jobs. In a flow shop or a Progressive type FMS, scheduling problem involves sequencing of ‘n’ jobs on ‘m’ machines with minimum ...
Gidhi, Pradyumna Kumar
core
A scheduling theory framework for GPU tasks efficient execution [PDF]
, 2018 Concurrent execution of tasks in GPUs can reduce the computation time of a workload by overlapping data transfer and execution commands.
A Allahverdi +11 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A hybrid job-shop scheduling system [PDF]
The intention of the scheduling system developed at the Fraunhofer-Institute for Material Flow and Logistics is the support of a scheduler working in a job-shop.
Bayat-Sarmadi, Fahid +3 more
core +1 more source
New efficient constructive heuristics for the hybrid flowshop to minimise makespan: A computational evaluation of heuristics [PDF]
, 2018 This paper addresses the hybrid flow shop scheduling problem to minimise makespan, a well-known scheduling problem for which many constructive heuristics have been proposed in the literature. Nevertheless, the state of the art is not clear due to partial
Fernández-Viagas Escudero, Víctor +2 more
core