Results 41 to 50 of about 84,491 (259)
Bottleneck adjacent matching heuristics for scheduling a re-entrant flow shop with dominant machine problem [PDF]
, 2009 The re-entrant flow shop environment has become prominent in the manufacturing industries and has recently attracted researchers attention. Typical examples of re-entrant flow shops are the printed circuit board manufacturing and furniture painting
Sh Ahmad, Sh Salleh
core
Mixed integer linear programming models for Flow Shop Scheduling with a demand plan of job types [PDF]
, 2018 This is a post-peer-review, pre-copyedit version of an article published in Central european journal of operations research. The final authenticated version is available online at: http://www.doi.org/10.1007/s10100-018-0553-8This paper presents two mixed
Alfaro Pozo, Rocío +1 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Multiple bottlenecks sorting criterion at initial sequence in solving permutation flow shop scheduling problem [PDF]
, 2021 This paper proposes a heuristic that introduces the application of bottleneck-based concept at the beginning of an initial sequence determination with the objective of makespan minimization.
A. S., Zainudin +3 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Bottleneck-based heuristic for three-machine flow shop scheduling [PDF]
, 2011 This paper considers a 3 machine flow shop (M1M2M3) with tendency of dominant (bottleneck) machine at M1. The developed bottleneck based heuristics from previous studies are considered in this case by Hezzeril (2010) and Irwan (2010), but were only ...
Abdul Rahim, Mohd Salleh
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A decomposition based algorithm for flexible flow shop scheduling with machine breakdown [PDF]
, 2009 Research on flow shop scheduling generally ignores uncertainties in real-world production because of the inherent difficulties of the problem. Scheduling problems with stochastic machine breakdown are difficult to solve optimally by a single approach ...
Choi, SH, Wang, K
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source