Results 61 to 70 of about 84,491 (259)
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Multiprocessor task scheduling in multistage hyrid flowshops: a genetic algorithm approach [PDF]
This paper considers multiprocessor task scheduling in a multistage hybrid flow-shop environment. The objective is to minimize the make-span, that is, the completion time of all the tasks in the last stage.
Davis L +6 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Modelling and solving train scheduling problems under capacity constraints [PDF]
Many large coal mining operations in Australia rely heavily on the rail network to transport coal from mines to coal terminals at ports for shipment. Over the last few years, due to the fast growing demand, the coal rail network is becoming one of the ...
Liu, Shi-Qiang
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Efficiency of the solution representations for the hybrid flow shop scheduling problem with makespan objective [PDF]
In this paper we address the classical hybrid flow shop scheduling problem with makespan objective. As this problem is known to be NP-hard and a very common layout in real-life manufacturing scenarios, many studies have been proposed in the literature to
Fernández-Viagas Escudero, Víctor +2 more
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Efficient heuristics for the hybrid flow shop scheduling problem with missing operations [PDF]
In this paper, we address the hybrid flowshop scheduling problem for makespan minimisation. More specifically, we are interested in the special case where there are missing operations, i.e.
Dios, Manuel +2 more
core
A simheuristic algorithm for solving an integrated resource allocation and scheduling problem [PDF]
Modern companies have to face challenging configuration issues in their manufacturing chains. One of these challenges is related to the integrated allocation and scheduling of resources such as machines, workers, energy, etc.
Ferone, Daniele +4 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source

