Results 61 to 70 of about 85,049 (338)

Flow shop scheduling with earliness, tardiness and intermediate inventory holding costs [PDF]

, 2003
We consider the problem of scheduling customer orders in a flow shop with the objective of minimizing the sum of tardiness, earliness (finished goods inventory holding) and intermediate (work-in-process) inventory holding costs. We formulate this problem
Bulbul, Kerem, Bülbül, Kerem, Kaminsky, Philip, Yano, Candace   +3 more
core   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

MODEL PENJADWALAN BACKWARD HYBRID FLOW SHOP 2 STAGE UNTUK MEMINIMASI MEAN FLOWTIME

Jurnal Lebesgue
The scheduling problem is a common challenge when it comes to executing tasks, making the resolution of this issue crucial for decision-making in production activities.
Asep Anwar, Rendiyatna Ferdian, Didit Damur Rochman   +2 more
doaj   +1 more source

Multi-Objective Hybrid Metaheuristic Search Algorithm for Distributed Reentrant Permutation Flow Shop Scheduling Via Considering Preventive Maintenance under Uncertainty [PDF]

مدیریت تولید و عملیات, 2018
: Distributing the production activities among the supply chain facilities with regard to the considered criteria can have a significant impact on the productive management. In this paper, a comprehensive mathematical model for reentrant permutation flow
Ali akbar Hasani
doaj   +1 more source

Bottleneck-based heuristic for three-machine flow shop scheduling [PDF]

, 2011
This paper considers a 3 machine flow shop (M1M2M3) with tendency of dominant (bottleneck) machine at M1. The developed bottleneck based heuristics from previous studies are considered in this case by Hezzeril (2010) and Irwan (2010), but were only ...
Abdul Rahim, Mohd Salleh
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Particle swarm optimization applied to job shop scheduling [PDF]

, 2007
In this project we have to apply the particle swarm optimization algorithm to job shop scheduling problem. Job shop scheduling is a combinatorial optimization problem where we have to arrange the jobs which may or may not be processed in every machine in
Dwivedi , Piyush, Vishal , Vivek
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

No idle flow shop scheduling models for optimization of machine rental costs with processing and separated setup times

Frontiers in Applied Mathematics and Statistics
Scheduling is one of the many skills required for advancement in today’s modern industry. The flow-shop scheduling problem is a well-known combinatorial optimization challenge. Scheduling issues for flow shops are NP-hard and challenging.
Shakuntla Singla, Harshleen Kaur, Deepak Gupta, Umar Muhammad Modibbo, Jatinder Kaur   +4 more
doaj   +1 more source