Results 121 to 130 of about 2,693,773 (355)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Effects of electrical pulse on metal deformation behaviors

open access: yesMaterials Research Express
As a kind of special energy field assisted plastic forming, electric pulse assisted plastic forming combines multiple physical fields, such as thermal, electrical, magnetic and mechanical effects, has multiple effects on metal.
Tao Huang   +7 more
doaj   +1 more source

Forces prediction in micro-grinding single-crystal copper considering the crystallographic orientation

open access: yesManufacturing Review, 2018
In the micro-grinding of single-crystal copper, the effect of crystallography becomes significant as the wheel works intra-crystalline. To quantify the effect of crystallographic orientation (CO) related to the cutting direction on the micro-grinding ...
Zhao Man   +3 more
doaj   +1 more source

Constitutive Equation of Hot Deformation of ZL114A Alloy

open access: yesJournal of Harbin University of Science and Technology, 2018
At the condition of deformation temperature of 350 ~ 470 ℃,strain rate of 0. 001 ~ 10 s -1, deformation of 50%,hot compression tests for ZL114A alloy were carried out by Gleeble-1500D thermal simulation testing machine. The characteristics of true stress-
KANG Fu-wei   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Study on constitutive models of hot deformation for 34CrNi3MoV steel

open access: yesMetalurgija, 2023
Isothermal constant strain rate compression experiments were conducted on 34CrNi3MoV steel using a thermal simulation experimental machine to study its thermal deformation behavior, with deformation temperatures ranging from 800 - 1 200 °C and strain ...
B. Zheng   +5 more
doaj  

BED SHEAR STRESS IN UNSTEADY FLOW [PDF]

open access: diamond, 2011
Paul Guard   +2 more
openalex   +1 more source

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