Results 111 to 120 of about 2,693,773 (355)

Time and flow stress dependences of internal stress during stress relaxation

open access: yesProcedia Manufacturing, 2018
Abstract Stress relaxation is a potential cause of formability improvement. To describe stress relaxation, the measurement of internal stress is essential. We investigated the time and flow stress dependences of the internal stress by conducting a strain-rate-change test and stress-dip test.
Yoshinori Kusuda   +8 more
openaire   +1 more source

A continuum model for dislocation dynamics in three dimensions using the dislocation density potential functions and its application in understanding the micro-pillar size effect

open access: yes, 2015
In this paper, we present a dislocation-density-based three-dimensional continuum model, where the dislocation substructures are represented by pairs of dislocation density potential functions (DDPFs), denoted by $\phi$ and $\psi$.
Xiang, Yang, Zhu, Yichao
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Bottom shear stress in unsteady sewer flow

open access: yesWater Science and Technology, 2006
The properties of unsteady open-channel turbulent flow were theoretically and experimentally investigated in a circular cross section channel with fixed sediment deposits. Velocity and turbulence distribution data were obtained using an ultrasonic velocity profiler (UVP). Different uniform flow conditions and triangular-shaped hydrographs were analysed.
V, Bares, J, Jirák, J, Pollert
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Slow flows of yield stress fluids: complex spatio-temporal behaviour within a simple elasto-plastic model

open access: yes, 2004
A minimal athermal model for the flow of dense disordered materials is proposed, based on two generic ingredients: local plastic events occuring above a microscopic yield stress, and the non-local elastic release of the stress these events induce in the ...
Armand Ajdari   +5 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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