This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Flow Stress Modeling using the Material Constitutive Model of Modified Zerilli-Armstrong
Hong Yu, Zhenzhen Shao, Facai Ren
openalex +1 more source
Effect of Hematocrit on Wall Shear Stress for Blood Flow through Tapered Artery [PDF]
Anurag Singh, D. P. Singh
openalex +1 more source
Two new mathematical models to predict the flow stress at hot deformation
Based on both linear and non-linear estimations of work hardening rate versus strain curves, two mathematical models have been developed to predict the flow curves under hot working conditions up to the peak.
Solhjoo, Soheil
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Constitutive Models for Dynamic Strain Aging in Metals: Strain Rate and Temperature Dependences on the Flow Stress. [PDF]
Song Y +3 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
New Constitutive Model for the Size Effect on Flow Stress Based on the Energy Conservation Law. [PDF]
Wang C +6 more
europepmc +1 more source
Dynamic flow and shear stress as key parameters for intestinal cells morphology and polarization in an organ-on-a-chip model [PDF]
Chiara Fois +3 more
openalex +1 more source

