Results 191 to 200 of about 2,693,773 (355)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Constitutive equations of AA6111 aluminum alloy

Metalurgija, 2019
The hot compression test was conducted in Gleeble-1 500D to study the hot flow stress behavior of AA6 111 aluminum alloy belonging to Al-Mg-Si series, at the deformation temperatures ranging from 350 to 500 °C and strain rates ranging from 0,01 s-1 to 1 ...
B. Z. Wang, X. M. Huang, C. Wang, Z. Y. Wang, C. Xing, H. C. Ji   +5 more
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Correlation among the Power Dissipation Efficiency, Flow Stress Course, and Activation Energy Evolution in Cr-Mo Low-Alloyed Steel. [PDF]

Materials (Basel), 2020
Opěla P, Schindler I, Kawulok P, Kawulok R, Rusz S, Navrátil H, Jurča R.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

The Influence of Fluidic Flow Stress on the Development of the Secondary Palate. [PDF]

J Dev Biol
Nagata M, Hayano S, Wang Z, Kosami T, Kamioka H.   +4 more
europepmc   +1 more source

Dislocation Density Based Flow Stress Model Applied to the PFEM Simulation of Orthogonal Cutting Processes of Ti-6Al-4V. [PDF]

Materials (Basel), 2020
Rodríguez JM, Larsson S, Carbonell JM, Jonsén P.   +3 more
europepmc   +1 more source

Ceil Remodelling by Mechanical Stress. Signal Flow from Mechanosensation to Cell Response.

, 2000
Masahiro Sokabe
openalex   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

A numerical integrated flow-stress processing model for plain weave textile composites. [PDF]

Sci Rep
Chen W, Zhang B.
europepmc   +1 more source