Results 41 to 50 of about 653,817 (263)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

VMetaFlow: A Meta-Framework for Integrating Visualizations in Coordinated View Applications

IEEE Access, 2022
The analysis and exploration of complex data sets are common problems in many areas, including scientific and business domains. This need has led to substantial development of the data visualization field. In this paper, we present VMetaFlow, a graphical
Nicusor Cosmin-Toader, Fernando Trincado-Alonso, Luis Pastor, Marcos Garcia-Lorenzo   +3 more
doaj   +1 more source

Multiresolution Flow Visualization. [PDF]

, 2001
Flow visualization has been an active research field for several years and various techniques have been proposed to visualize vector fields, streamlines and textures being the most effective and popular ones. While streamlines are suitable to get rough information on the behavior of the flow, textures depict the flow properties at the pixel level ...
Jobard, Bruno, Lefer, Wilfrid
openaire   +1 more source

Flow: Statistics, visualization and informatics for flow cytometry [PDF]

Source Code for Biology and Medicine, 2008
Abstract Flow is an open source software application for clinical and experimental researchers to perform exploratory data analysis, clustering and annotation of flow cytometric data. Flow is an extensible system that offers the ease of use commonly found in commercial flow cytometry software packages and the statistical power of
Jacob Frelinger, Thomas B. Kepler, Cliburn Chan   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bioinspired Propulsion Mechanism Using a Fin with a Dynamic Variable-Effective-Length Spring

Journal of Biomechanical Science and Engineering, 2009
Since the propulsion mechanism in fluid using an elastic fin, such as the caudal fin or the pectoral fin of fish, is effective, a number of studies have examined the use of elastic fins for propulsion in water and the development of fish robots using ...
Masataka NAKABAYASHI, Reiji KOBAYASHI, Shunichi KOBAYASHI, Hirohisa MORIKAWA   +3 more
doaj   +1 more source

An adaptive LIC based geographic flow field visualization method by means of rotation distance

International Journal of Digital Earth, 2023
Geographic visualization is essential for explaining and describing spatiotemporal geographical processes in flow fields. However, due to multi-scale structures and irregular spatial distribution of vortices in complex geographic flow fields, existing ...
Yulin Ding, Daiyu Shang, Tingchen Wu, Qing Zhu, Liguo Zhang, Yongxin Guo   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Non-invasive and fully two-dimensional quantitative visualization of transparent flow fields enabled by photonic spin-decoupled metasurfaces

Light: Science & Applications
Transparent flow field visualization techniques play a critical role in engineering and scientific applications. They provide a clear and intuitive means to understand fluid dynamics and its complex phenomena, such as laminar flow, turbulence, and ...
Qingbin Fan, Peicheng Lin, Le Tan, Chunyu Huang, Feng Yan, Yanqing Lu, Ting Xu   +6 more
doaj   +1 more source