Results 61 to 70 of about 4,348,404 (302)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

VMetaFlow: A Meta-Framework for Integrating Visualizations in Coordinated View Applications

IEEE Access, 2022
The analysis and exploration of complex data sets are common problems in many areas, including scientific and business domains. This need has led to substantial development of the data visualization field. In this paper, we present VMetaFlow, a graphical
Nicusor Cosmin-Toader, Fernando Trincado-Alonso, Luis Pastor, Marcos Garcia-Lorenzo   +3 more
doaj   +1 more source

Flow: Statistics, visualization and informatics for flow cytometry [PDF]

Source Code for Biology and Medicine, 2008
Abstract Flow is an open source software application for clinical and experimental researchers to perform exploratory data analysis, clustering and annotation of flow cytometric data. Flow is an extensible system that offers the ease of use commonly found in commercial flow cytometry software packages and the statistical power of
Jacob Frelinger, Thomas B. Kepler, Cliburn Chan   +2 more
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

EMDialog : bringing information visualization into the museum [PDF]

, 2015
Digital interactive information displays are becoming more common in public spaces such as museums, galleries, and libraries. However, the public nature of these locations requires special considerations concerning the design of information visualization
Schmidt, Holly, Hinrichs, Uta, Carpendale, Sheelagh   +2 more
core   +1 more source

Comparison of the Viscous Liquids Spraying by the OIG and the Oil Configurations of an Effervescent Atomizer at Low Inlet Pressures

Journal of Mechanical Engineering, 2016
In this work we studied the influence of the fluid injection configuration (OIG: outside-in-gas, OIL: outside-in-liquid) on the internal flows and external sprays parameters.
Mlkvik Marek, Olšiak Róbert, Smolar Marek   +2 more
doaj   +1 more source

Stable Algorithm Based On Lax-Friedrichs Scheme for Visual Simulation of Shallow Water

Emitter: International Journal of Engineering Technology, 2020
Many game applications require fluid flow visualization of shallow water, especially dam-break flow. A Shallow Water Equation (SWE) is a mathematical model of shallow water flow which can be used to compute the flow depth and velocity.
Bandung Arry Sanjoyo, Mochamad Hariadi, Mauridhi Hery Purnomo   +2 more
doaj   +1 more source

An adaptive LIC based geographic flow field visualization method by means of rotation distance

International Journal of Digital Earth, 2023
Geographic visualization is essential for explaining and describing spatiotemporal geographical processes in flow fields. However, due to multi-scale structures and irregular spatial distribution of vortices in complex geographic flow fields, existing ...
Yulin Ding, Daiyu Shang, Tingchen Wu, Qing Zhu, Liguo Zhang, Yongxin Guo   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source