Results 111 to 120 of about 31,225 (293)

Manufacturing of Composites by Pressure Infiltration, Structure and Mechanical Properties [PDF]

, 2008
This paper presents the possibility of composite block production by using pressure infiltration technology. This method uses the pressure of an inert gas (usually argon or nitrogen) to force the melted matrix material to infiltrate the reinforcing ...
Dobránszky, János, Németh, Árpád, Orbulov, Imre Norbert   +2 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Effects of formulation on flowability of selected herbal powders using compendial methods and powder flow analyser [PDF]

, 2016
This study was aimed at investigating the effects of formulation on flowability of selected herbal powders which include Labisia pumila, Ortosiphon stamineus, Eurycoma longifolia and Andrographis paniculata using compendial methods and a recently ...
Chin, Nyuk Ling, Etti, Christopher Joseph, Mohd Tahir, Suraya, Yusof, Yus Aniza   +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Size, shape and flow of powders for use in Selective Laser Sintering (SLS) [PDF]

, 2014
6th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 1-5 October 2013This paper investigates the effects of particles size and morphology on flowability of a range of polymeric powders (SLS and non-SLS ...
Anderson, A., Berretta, Silvia, Evans, Kenneth E., Ghita, O., Newman, C.   +4 more
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Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Kompetensi pembimbing syarikat bertauliah Sistem Latihan Dual Nasional (SLDN) [PDF]

, 2015
Sistem Latihan Dual Nasional (SLDN) merupakan satu sistem latihan dan usahasama antara sektor awam dan sektor swasta dilaksanakan untuk melahirkan tenaga mahir k-worker selari dengan keperluan industri masa kini untuk membangunkan ekonomi negara.
Md.Jizat, Nor Atikah
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Control of the injectability of calcium carbonate-calcium phosphate mixed cements for bone reconstruction [PDF]

, 2009
The purpose of this study was to improve injectability and cohesiveness of original calcium carbonate-calcium phosphate mixed (CaCO3-CaP) self-setting paste for bone filling and repair.
Combes, Christèle, Girod-Fullana, Sophie, Le Bolay, Nadine, Rey, Christian, Tadier, Solène   +4 more
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