Results 71 to 80 of about 275,010 (282)
The Multiresolution Analysis of Flow Graphs [PDF]
, 2019 WoLLIC 2019; 19 pages.
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Aspects of organizing game interactions among asymmetric agents using graph neural networks
Научно-технический вестник информационных технологий, механики и оптикиThe article considers the structures of representation of the graph of inter-agent connections for increasing the efficiency of agent interaction in cooperative competitive games using graph neural networks.
A. O. Isakov +4 more
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Nauka ta progres transportu, 2020 Purpose. The purpose of the article is to develop a universal unified parallel synchronous algorithm for the implementation of tasks for calculation of maximum one- and multicommodity flows, as well as the creation of a software complex that provides the
V. V. Skalozub +2 more
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Simulation Studies of Link Group in Elastic Optical Networks Used in Internet of Things Solutions
Transport and Telecommunication, 2023 The elastic optical network (EON) solution is the most flexible in terms of allocation of resources for various traffic streams transported in core part (edge-cloud) of Internet of Things (IoT) networks.
Głąbowski Mariusz, Sobieraj Maciej
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Provably Correct Control-Flow Graphs from Java Programs with Exceptions [PDF]
, 2011 We present an algorithm to extract flow graphs from Java bytecode, focusing on exceptional control flows. We prove its correctness, meaning that the behaviour of the extracted control-flow graph is an over-approximation of the behaviour of the original ...
Amighi, Afshin +2 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Integrated development of carrying capacities of the Baikal-Amur Mainline and Trans-Siberian Railway
MATEC Web of Conferences, 2018 The paper considers actual technical and technological problems in the development of the Eastern polygon of the Russian railway network. The purpose of the study is to develop a methodology and software tools that ensure the search for effective ...
Borodin Andrey +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source