Results 61 to 70 of about 275,010 (282)
Morphological PDEs on Graphs for Image Processing on Surfaces and Point Clouds
Partial Differential Equations (PDEs)-based morphology offers a wide range of continuous operators to address various image processing problems. Most of these operators are formulated as Hamilton–Jacobi equations or curve evolution level set and ...
Abderrahim Elmoataz +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Testing flow graph reducibility [PDF]
Many problems in program optimization have been solved by applying a technique called interval analysis to the flow graph of the program. A flow graph which is susceptible to this type of analysis is called reducible. This paper describes an algorithm for testing whether a flow graph is reducible.
openaire +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Transforming SHACL Shape Graphs into HTML Applications for Populating Knowledge Graphs
Creating applications to manually populate and modify knowledge graphs is a complex task. In this paper, we propose a novel approach for designing user interfaces for this purpose, based on existing SHACL constraint files.
Petko Rutesic +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Inhomogeneous percolation models for spreading phenomena in random graphs
Percolation theory has been largely used in the study of structural properties of complex networks such as the robustness, with remarkable results.
Dall'Asta, Luca
core +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Maximal Graphs and Spacelike Mean Curvature Flows in Semi-Euclidean Spaces [PDF]
Two main results are proved. The first is for the maximal graph system in semi-Euclidean spaces. Existence of smooth solutions to the Dirichlet problem is proved, under certain assumptions on the boundary data.
THORPE, BENJAMIN,STUART
core

