Results 211 to 220 of about 99,394 (285)

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

Deucravacitinib Inhibits Synovial Fibroblast Activation Via TYK2/STAT3 and PI3K/Akt Signaling Pathway. [PDF]

Inflammation
Qu Z, Wang J, Wang X, Mo L, Li H, Liu X, Chai X, Yan L, Li Y.   +8 more
europepmc   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Metrnl/Meteorin-like/IL-41 Alleviates Rheumatoid Arthritis Via PPARγ-Mediated Suppression of Inflammation, Angiogenesis, and Bone Destruction. [PDF]

Inflammation
Sun T, Xia L, Li Y, Zhao M, Li Z, Shen H.   +5 more
europepmc   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

The Critical Role of Follow-Up in Fracture Liaison Services for Geriatric Hip Fracture Patients: A Retrospective Cohort Study. [PDF]

Geriatr Orthop Surg Rehabil
Israeli Eilon N, Fisher Negev T, Eilon E, Alami M, Israel R, Olshinka N, Or O.   +6 more
europepmc   +1 more source

Axial F–Bi–Ov Electron Pump Drives Continuous Reconfiguration of Bi Sites for Efficient Photocatalytic N2 Reduction

Advanced Science, EarlyView.
Axial Fluorine and Light‐Induced Oxygen Vacancies Synergize as an Electron Pump to Lower N2 Activation Energy and Enable Sustained NH3 Synthesis on FBWO. ABSTRACT The electronic structure precision of single‐atom catalysts (SACs) represents a decisive factor limiting advancements in photocatalytic nitrogen reduction (NRR) efficiency.
Xiao Ge, Xinyi Wu, Hao‐tong Li, Xinya Liu, Jie‐jie Chen, Yuan Min, Xiaozhi Wang   +6 more
wiley   +1 more source

Liposomal CRISPR/Cas9-Mediated Local Genome Editing for Joint Disease in Mucopolysaccharidosis Type I. [PDF]

Pharmaceutics
Santos HS, Poletto E, Vera LNP, Farinon M, Kubaski F, Carneiro PB, Carniel WDS, Giugliani R, Matte U, Teixeira HF, Schuh RS, Baldo G.   +11 more
europepmc   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

HDACs targeting from traditional Chinese medicine: mechanisms and therapeutic potential in rheumatoid arthritis. [PDF]

Front Pharmacol
Sun C, Lv S.
europepmc   +1 more source