Results 211 to 220 of about 30,676 (298)

TNF-driven intracellular complement factor H-NF-κB feed-forward loop amplifies inflammatory mediator production in rheumatoid arthritis synovial fibroblasts. [PDF]

Inflamm Regen
Kobayashi H, Mokuda S, Ishitoku M, Watanabe H, Sugimoto T, Yoshida Y, Masumoto J, Hirata S.   +7 more
europepmc   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

How I Do It: OpenTrainer, An Open-Source Laparoscopic Surgery Simulator With a Smartphone Endoscope. [PDF]

J Surg Educ
Nandakumar A, Hudock MR, Daly GW, Diane M, Shah M, Tavakol DN, Vunjak-Novakovic G.   +6 more
europepmc   +1 more source

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

Advanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang, Sang Mok Park, Dawn Meyer, Seul Ah Lee, Yumin Dai, Tianhao Yu, Taewoong Park, Feiyang Li, Jason Gerard Jedlicka, Tristan Michael Long, Oluwabunmi T. Oladele, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Young L. Kim, Chi Hwan Lee   +15 more
wiley   +1 more source

Usual dietary intake estimation in the German National Cohort (NAKO). [PDF]

Front Nutr
Wawro N, Gastell S, Mikolajczyk R, Glaser N, Schlesinger S, Schikowski T, Karch A, Teismann H, Obi N, Harth V, Weber KS, Övermöhle C, Leitzmann M, Fischer B, Pischon T, Nimptsch K, Schmidt B, Völzke H, Ittermann T, Peters A, Thorand B, Hebestreit A, Wolters M, Katzke V, Jaskulski S, Sekula P, Krist L, Willich SN, Holleczek B, Hoffmeister M, Klett-Tammen C, Meyerdierks D, Wirkner K, Conrad J, Nöthlings U, Schulze MB, Linseisen J, Knüppel S.   +37 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Genotoxic stressors mimicking synovial microenvironment modulate B cell fate in RA-FLS co-culture. [PDF]

Front Immunol
Bruci D, Lowin T, Fritz G, Wolf F, Pongratz G.   +4 more
europepmc   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source