Directed Evolution of FLS2 towards Novel Flagellin Peptide Recognition. [PDF]
PLoS ONE, 2016 Microbe-associated molecular patterns (MAMPs) are molecules, or domains within molecules, that are conserved across microbial taxa and can be recognized by a plant or animal immune system.
Laura Helft +2 more
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FLS2-BAK1 extracellular domain interaction sites required for defense signaling activation. [PDF]
PLoS ONE, 2014 Signaling initiation by receptor-like kinases (RLKs) at the plasma membrane of plant cells often requires regulatory leucine-rich repeat (LRR) RLK proteins such as SERK or BIR proteins.
Teresa Koller, Andrew F Bent
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Arabidopsis heterotrimeric G proteins regulate immunity by directly coupling to the FLS2 receptor
eLife, 2016 The Arabidopsis immune receptor FLS2 perceives bacterial flagellin epitope flg22 to activate defenses through the central cytoplasmic kinase BIK1. The heterotrimeric G proteins composed of the non-canonical Gα protein XLG2, the Gβ protein AGB1, and the ...
Xiangxiu Liang +11 more
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eLife, 2023 The Arabidopsis thaliana FLAGELLIN-SENSITIVE2 (FLS2), a typical receptor kinase, recognizes the conserved 22 amino acid sequence in the N-terminal region of flagellin (flg22) to initiate plant defense pathways, which was intensively studied in the past ...
Yaning Cui +9 more
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Shoot Maturation Strengthens FLS2-Mediated Resistance toPseudomonas syringae
Molecular Plant-Microbe Interactions®, 2023 Temporospatial regulation of immunity components is essential for properly activating plant defense response. Flagellin-sensing 2 (FLS2) is a surface-localized receptor that recognizes bacterial flagellin. The immune function of FLS2 is compromised in early stages of shoot development.
Lanxi Hu +3 more
openaire +5 more sources
Membranes, 2023 Plant cell signaling often relies on the cellular organization of receptor-like kinases (RLKs) within membrane nanodomains to enhance signaling specificity and efficiency. Thus, nanometer-scale quantitative analysis of spatial organizations of RLKs could
Jeremiah Traeger +4 more
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Stem-cell-triggered immunity through CLV3p–FLS2 signalling [PDF]
Nature, 2011 Stem cells in the shoot apical meristem (SAM) of plants are the self-renewable reservoir for leaf, stem and flower organogenesis. In nature, disease-free plants can be regenerated from SAM despite infections elsewhere, which underlies a horticultural practice for decades. However, the molecular basis of the SAM immunity remains unclear.
Horim, Lee, Ok-Kyong, Chah, Jen, Sheen
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Induced Endocytosis of the Receptor Kinase FLS2 [PDF]
Plant Signaling & Behavior, 2006 Receptor-like kinases (RLKs) that function as pattern-recognition receptors (PRRs) play a key role in plant immune responses. The receptor recognizing flagellin in Arabidopsis, FLS2, is encoded by a membrane resident RLK. FLS2 is involved in preinvasive immunity against bacterial infection.
Salomon, S., Robatzek, S.
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Probing the Arabidopsis Flagellin Receptor: FLS2-FLS2 Association and the Contributions of Specific Domains to Signaling Function [PDF]
The Plant Cell, 2012 Flagellin sensing2 (FLS2) is a transmembrane receptor kinase that activates antimicrobial defense responses upon binding of bacterial flagellin or the flagellin-derived peptide flg22. We find that some Arabidopsis thaliana FLS2 is present in FLS2-FLS2 complexes before and after plant exposure to flg22.
Sun, W. X. +5 more
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Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to Ralstonia flg22 and activation of anti‐bacterial immunity [PDF]
Plant Biotechnology JournalLi M, Chen Y, Wei Y, Macho AP.
exaly +2 more sources