Results 221 to 230 of about 559,755 (305)

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

Advanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys, Jaimee‐Lee Wood, James I. Novak, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Mark C. Allenby   +6 more
wiley   +1 more source

Persistence and spread of fluconazole-resistant <i>Candida parapsilosis</i> clinical isolates associated with increased <i>ERG11</i> copies in Qatar. [PDF]

Microb Genom
Zhang Z, Wang Y, Ben Abid F, Salah H, Al Ismail K, Eldos H, Samuel B, Zhou R, Sundararaju S, Suleimen M, Wang K, Lee B, Al Maslamani M, Sultan AA, Perez-Lopez A, Xu J, Tsui CKM.   +16 more
europepmc   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

LSTM-Based Recurrent Neural Network Predicts Influenza-Like-Illness in Variable Climate Zones. [PDF]

Immun Inflamm Dis
Amendolara A, Gowans C, Barton J, Payne A, Sant D.   +4 more
europepmc   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

Advanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito, Byeongwook Jo, Tomohiro Morita, Shota Noda, Minghao Nie, Shoji Takeuchi   +5 more
wiley   +1 more source

Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness - United States, September 2025-February 2026.

MMWR Morb Mortal Wkly Rep
Maloney P, Reeves EL, Wielgosz K, Price AM, Natarajan K, DeSilva MB, Dascomb K, Klein NP, Tartof SY, Irving SA, Grannis SJ, Ong TC, Weber ZA, Schuster JE, Zerr DM, Michaels MG, Boom JA, Halasa NB, Staat MA, Weinberg GA, House SL, Saade EA, Geffel KM, Gaglani M, Wernli KJ, Murugan V, Martin ET, Bontrager NAB, Kirby MK, Payne AB, Dawood FS, Tannis A, Moline HL, Zhao SK, Adams K, DeCuir J, Olson SM, Chung JR, Lewis N, Flannery B, Reed C, Garg S, Ellington S, CDC Influenza Vaccine Effectiveness Collaborators, CDC Influenza Vaccine Effectiveness Collaborators.   +44 more
europepmc   +1 more source

Anxiolytic and antidepressant effects of astaxanthin: behavioral and mechanistic insights in a rat model. [PDF]

Front Pharmacol
Ranjbari M, Fakhri S, Abbaszadeh F, Kiani A, Mohammadi-Noori E, Echeverría J.   +5 more
europepmc   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

A Dissolving Microneedle Design for Poorly Water-Soluble Drugs for Enhanced Skin Permeation and Transdermal Delivery Fabricated Using 3D Printing. [PDF]

Micromachines (Basel)
Jin SG.
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source