Results 21 to 30 of about 9,790 (202)

Synergistic effect of low‐frequency ultrasound and antibiotics on the treatment of Klebsiella pneumoniae pneumonia in mice

Microbial Biotechnology, Volume 15, Issue 11, Page 2819-2830, November 2022., 2022
In the present in vivo study, we provide evidence showing that LFU can improve the efficacy of meropenem (MEM) or amikacin (AMK) in Kp pneumonia model. LFU combined with antibiotics significantly improved the survival state of mice, decrease the counts per second (CPS), accelerated the clearance of bacteria and reduced inflammatory injury of lung.
Kaicheng Yan, Tianli Yang, Juan Xu, Liuhan Dong, Jin Wang, Yun Cai   +5 more
wiley   +1 more source

Pharmakologie der Januskinase‐Inhibitoren – Teil 1: Pharmakokinetik

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 11, Page 1485-1500, November 2022., 2022
Zusammenfassung Der Einsatz von Januskinase‐Inhibitoren zur Therapie chronisch‐entzündlicher Erkrankungen etabliert sich zunehmend als Behandlungsoption in mehreren Indikationen. Um den klinischen Einsatz effizient zu gestalten, sind pharmakologische Kenntnisse zum JAK/STAT‐Signalweg zu den Besonderheiten der Pharmakokinetik der einzelnen Arzneistoffe ...
Adina Eichner, Johannes Wohlrab
wiley   +1 more source

Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients – 30 months follow‐up

Journal of Thrombosis and Haemostasis, Volume 20, Issue 5, Page 1166-1181, May 2022., 2022
Abstract Background There are no data on the effect of low‐dose anticoagulation as secondary prophylaxis for venous thromboembolism (VTE) in cancer patients. We assessed the efficacy and safety of low‐dose apixaban for 30 months, after initial 6 months of full‐dose treatment.
Trine‐Lise Larsen, Herish Garresori, Jorunn Brekke, Tone Enden, Hege Frøen, Eva Marie Jacobsen, Petter Quist‐Paulsen, Alina Carmen Porojnicu, Anne Hansen Ree, Dag Torfoss, Elin Osvik Velle, Hilde Skuterud Wik, Waleed Ghanima, Per Morten Sandset, Anders Erik Astrup Dahm   +14 more
wiley   +1 more source

Comparative efficacy of selenoureido carbonic anhydrase inhibitors and azole antifungal drugs against clinical isolates of Malassezia pachydermatis. [PDF]

Vet Dermatol
Background – Malassezia pachydermatis (MP) is implicated in severe dermatitis and otitis externa (OE) of companion animals and recently gained attention for its increasing resistance to azole compounds. For this reason, developing novel therapeutic strategies is of great interest. In a previous work, we used reference yeast isolates to evaluate several
Spadini C, Mezzasalma N, Odigie AE, Angeli A, Carta F, Selleri S, Gandolfo E, Taddei S, Franceschi V, Minesso S, Supuran CT, Cabassi CS.   +11 more
europepmc   +2 more sources

Kinetik der minimalen Hemmkonzentration verschiedener Antimykotika gegenüber den klinisch isolierten Erregern der Onychomykosen während einer Beobachtungszeit von 20 Wochen [PDF]

, 2003
Ziel dieser Studie war es zu zeigen, ob die Dermatophyten (Trichophyton rubrum und Trichophyton mentagrophytes) und der Schimmelpilz Scopulariopsis brevicaulis in Nagelspäne, die von Onychomykosepatienten isoliert wurden, unter ex-vivo ...
Straßmann, Kai, Straßmann, Kai
core   +1 more source

Investigação da Sensibilidade ao Fluconazol e Produção de Enzimas Hidrolíticas por Candida sp. Isoladas do Trato Respiratório de Pacientes Internados em um Hospital no Sul de Minas Gerais/Investigation of Fluconazole Sensibility and Hydrolytic Enzimes Pro

Revista Ciências em Saúde, 2012
Objetivo: Identificar e caracterizar isolados de Candida do trato respiratório de pacientes, em relação à sensibilidade ao fluconazol e produção de enzimas hidrolíticas (fosfolipase e proteinase).
Bruna Fernanda Fernandes Ferreira, Ligia Junqueira Ragazzini, Marileia Chaves Andrade   +2 more
doaj   +1 more source

Antimicrobial Properties of Strychnos phaeotricha (Loganiaceae) Liana Bark Secondary Metabolites at the Interface of Nanosilver Particles and Nanoencapsulation by Chitosan Transport Vehicles

Journal of Nanomaterials, Volume 2022, Issue 1, 2022., 2022
In this study, Strychnos phaeotricha liana bark extract was used as a metabolite container both on the surface of metallic nanosilver and encapsulated by a chitosan polymer. The plant extract was able to reduce Ag+ into Ag0 efficiently, and the encapsulation rate was determined.
Armel Florian Tchangou Njiemou, Awawou Paboudam Gbambie, Simone Veronique Fannang, Antoine Vayarai Manaoda, Vasily Gvilava, Alex Spieß, Gildas Fonye Nyuyfoni, Nelie Alida Mepoubong Kegne, Agnes Antoinette Ntoumba, Philippe Belle Ebanda Kedi, Bertin Sone Enone, Francis Ngolsou, Jean Yves Sikapi Fouda, Joel Olivier Avom Mbeng, Mesode Nnange Akweh, Armelle Michelle Houatchaing Kouemegne, Daniel Aurelien Yana, Geordamie Chimi, Alex Vincent Somba, Vandi Deli, Emmanuel Nnanga Nga, Francois Eya’ane Meva, Christoph Janiak, Lavinia Balan   +23 more
wiley   +1 more source

Rinite fúngica em equino Quarto de Milha: Relato de caso

Pubvet, 2023
A rinite fúngica em equinos é de ocorrência rara, ainda não se sabe ao certo como a etiopatogenia da doença funciona. Os fungos são conhecidos pelo seu caráter oportunista, e o uso indiscriminado de corticosteroides, antibióticos de amplo espectro e ...
Gabriel Lima de Almeida, Tatiana Passarine da Silva, Camilla Vieira Kegler, Ana Carolina Lemos Caldeira, Regina de Cassia Veronezi Veronezi   +4 more
doaj   +1 more source

Guidelines for the treatment of severe sepsis and septic shock: management of the infectious agent, source control and antimicrobial treatment [PDF]

, 2016
Sepsis is a common and lethal condition that carries a substantial financial burden. In addition, it is the main cause of death in intensive care units. Early diagnosis and treatment of patients has been clearly shown to improve prognosis.
Carvalho, Noemia Barbosa, Diament, Decio [UNIFESP], Machado, Flavia Ribeiro [UNIFESP], Rigatto, Otelo, Salomão, Reinaldo [UNIFESP], Silva, Brenda Nazaré Gomes da [UNIFESP], Silva, Eliezer   +6 more
core   +2 more sources

Real clinical impact of drug–drug interactions of immunosuppressants in transplant patients

Pharmacology Research &Perspectives, Volume 9, Issue 6, December 2021., 2021
Abstract The main objective was to determine the prevalence of real drug–drug interactions (DDIs) of immunosuppressants in transplant patients. We conducted a prospective, observational 1‐year study at a tertiary hospital, including all transplanted patients.
Ana Isabel Gago‐Sánchez, Pilar Font, Manuel Cárdenas, María Dolores Aumente, José Ramón Del Prado, Miguel Ángel Calleja   +5 more
wiley   +1 more source