Results 81 to 90 of about 459,232 (296)

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Novel coupling applicable in off-centered condition

Mechanical Engineering Journal, 2016
A novel coupling was devised by utilizing the self-locking property of a belt. The torque is transmitted through a flexible belt. The belt length between the power disk and the driven shaft varies with a rotation of shaft in an off-centered condition. It
Keiji IMADO, Kiyoshi TERADA
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Linear response theory and transient fluctuation theorems for diffusion processes: a backward point of view

, 2009
On the basis of perturbed Kolmogorov backward equations and path integral representation, we unify the derivations of the linear response theory and transient fluctuation theorems for continuous diffusion processes from a backward point of view.
Bochkov G N, Cameron R H, Chernyak V, Chetrite R, Fei Liu, Gardiner C W, Harris R J, Huan Tong, Kac M, Karatzas I, Kubo R, Kurchan J, Kurchan J, Liu F, Maes C, Risken H, Rui Ma, Smoluchowski M V, Speck T, Speck T, Speck T, Stroock D W, Zhong-can Ou-Yang, Zinn-Justin J   +23 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Nonlinear self-induced vibration and operability envelope analysis of production strings in marine natural gas development

International Journal of Naval Architecture and Ocean Engineering, 2019
Marine production strings are continuously affected by unstable internal fluid during operation. In this paper, the structural governing equation for marine production string self-induced vibration is constructed.
Kang Liu, Guoming Chen, Gaogeng Zhu, Jingyu Zhu   +3 more
doaj   +1 more source

Metrics Fluctuational Theory

, 2002
It is supposed the alternative to Quantum Mechanics Axiomatic. Fluctuational Theory save the Mathematics of Quantum Mechanic without change, naming this Mathematics as Method of Indirect Computation. Fluctuational Theory is delete the axiomatic of Quantum Mechanics and replaces it by the assumption of Gravitational Noise.
openaire   +2 more sources

Geometrical aspects and connections of the energy-temperature fluctuation relation

, 2009
Recently, we have derived a generalization of the known canonical fluctuation relation $k_{B}C=\beta^{2}$ between heat capacity $C$ and energy fluctuations, which can account for the existence of macrostates with negative heat capacities ...
Bohr N, Chavanis P H, Gross D H E, Heisenberg W, Kinchin A I, L Velazquez, Landau P D, Lynden-Bell D, Lynden-Bell D, Lynden-Bell D, Reichl L E, Rosenfeld L, S Curilef, Thirring W, Velazquez L, Velazquez L, Velazquez L   +16 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source