Results 1 to 10 of about 71,615 (220)
Numerical Simulation of a Submerged Floating Tunnel: Validation and Analysis
Applied SciencesThe dynamic response analysis of submerged floating tunnels (SFTs) under seismic action is a complex two-way fluid–structure coupling problem that requires expertise in structural dynamics, fluid mechanics, and advanced computational methods. The coupled
Hao Li, Xiaohui Cheng, Hua Pan
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AIP Advances, 2019 The air arc impinging to chamber shell during interruption current process were studied by experiments and numerical simulation. Firstly, strain characteristics of chamber shell were measured by the strain gauge, and the strain changing with times were ...
Yujie Wang, Lijun Wang, Shenli Jia
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Fluid–structure interaction study of three-dimensional vehicle model under crosswind
Advances in Mechanical Engineering, 2015 It is very important to study fluid–structure interaction of vehicles which move in strong crosswind environment. For solving a fluid–structure interaction problem, the effect of the deformation and vibration of the elastic body on the flow field should ...
Hui Zhu, Yang Zhigang
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Development of 6-way CFD-DEM-FEM momentum coupling interface using partitioned coupling approach
Results in EngineeringFluid-particle-structure interactions (FPSI) govern a wide range of natural and engineering phenomena, from landslides to erosion in abrasive water jet cutting nozzles. Despite the importance of studying FPSI, existing numerical frameworks often simplify
Prasad Adhav +2 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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Research Method of Wellbore Stability of Coal Formation in the Daniudi Gas Field
Shiyou jixie, 2015 Most studies on the coalbed wellbore stability are based on continuum mechanics,few research has involved fluid-structure coupling.The coal mechanical properties have been studied through the uniaxial and 3-axis compressive strength test of coal samples ...
Cheng Fushan +5 more
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