Results 41 to 50 of about 391,331 (237)

Hydro-micromechanical modeling of wave propagation in saturated granular media [PDF]

, 2018
Biot's theory predicts the wave velocities of a saturated poroelastic granular medium from the elastic properties, density and geometry of its dry solid matrix and the pore fluid, neglecting the interaction between constituent particles and local flow ...
Cheng, Hongyang, Harting, Jens, Luding, Stefan, Magnanimo, Vanessa, Rivas, Nicolás   +4 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Numerical Simulation of a Submerged Floating Tunnel: Validation and Analysis

Applied Sciences
The dynamic response analysis of submerged floating tunnels (SFTs) under seismic action is a complex two-way fluid–structure coupling problem that requires expertise in structural dynamics, fluid mechanics, and advanced computational methods. The coupled
Hao Li, Xiaohui Cheng, Hua Pan
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Computational evaluation of flight performance of flapping-wing nano air vehicles using hierarchical coupling of nonlinear dynamic and fluid-structure interaction analyses

Engineering Applications of Computational Fluid Mechanics, 2023
This study endeavours to introduce an inventive hierarchical coupling methodology for evaluating the flight capabilities of polymer micromachined flapping-wing nano air vehicles (FWNAVs) using advanced computational tools.
Rashmikant, M. Onishi, K. Sugikawa, D. Ishihara   +3 more
doaj   +1 more source

Numerical investigation of fluid structure interaction between unsteady flow and vibrating liner in a combustion chamber [PDF]

, 2007
Numerical investigations of fluid structure interaction between unsteady flow\ud and vibrating liner in a combustion chamber are undertaken. The computational study consist of two approaches.
Cooper, R.K., Khatir, Z., Kok, J.B.W., Pozarlik, A.K., Watterson, J.W.   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Fluid–structure interaction study of three-dimensional vehicle model under crosswind

Advances in Mechanical Engineering, 2015
It is very important to study fluid–structure interaction of vehicles which move in strong crosswind environment. For solving a fluid–structure interaction problem, the effect of the deformation and vibration of the elastic body on the flow field should ...
Hui Zhu, Yang Zhigang
doaj   +1 more source

Stochastic Eulerian Lagrangian Methods for Fluid-Structure Interactions with Thermal Fluctuations

, 2010
We present approaches for the study of fluid-structure interactions subject to thermal fluctuations. A mixed mechanical description is utilized combining Eulerian and Lagrangian reference frames.
Alberts, Arienti, Armstrong, Atzberger, Atzberger, Banchio, Bedeaux, Bodard, Brady, Braescu, Chen, Da Prato, Danuser, De Fabritiis, Doi, Donev, Dowell, Eijkel, Ermak, Fisher, Fung, G Larson, Garcia, Gardiner, Gelfand, Givelberg, Gotter, Gottlieb, Griffith, Hauge, Hills, Kim, Kloeden, Kramer, Landau, Lebedev, Lieb, Lim, Mazur, Mezei, Miller, Mittal, Moffitt, Oksendal, Paul J. Atzberger, Peskin, Peskin, Purcell, Reichert, Reichl, Rotne, Saintillan, Squires, Strang, Strang, Strikwerda, Trefethen, Tuckerman, Valentine, Wang, Watari, Watson, Yamakawa, Zohdi   +63 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source