Results 51 to 60 of about 195,182 (264)

Numerical Simulation of a Submerged Floating Tunnel: Validation and Analysis

Applied Sciences
The dynamic response analysis of submerged floating tunnels (SFTs) under seismic action is a complex two-way fluid–structure coupling problem that requires expertise in structural dynamics, fluid mechanics, and advanced computational methods. The coupled
Hao Li, Xiaohui Cheng, Hua Pan
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Fluid–structure interaction study of three-dimensional vehicle model under crosswind

Advances in Mechanical Engineering, 2015
It is very important to study fluid–structure interaction of vehicles which move in strong crosswind environment. For solving a fluid–structure interaction problem, the effect of the deformation and vibration of the elastic body on the flow field should ...
Hui Zhu, Yang Zhigang
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analytical modeling of rotor-structure coupling using modal decomposition for the structure and the blades. [PDF]

, 2014
This paper presents a linear semi-analytical model that is able to predict complex rotor-structure coupling phenomena and their stability. It was primarily designed so as to gain a better physical understanding of this kind of aeroelastic instabilities ...
ROUCOULES, Lionel, CRANGA, Paul, ROUCHON, Thibaut, MALBURET, François   +3 more
core  

Fluid simulations with atomistic resolution : a hybrid multiscale method with field-wise coupling [PDF]

, 2013
We present a new hybrid method for simulating dense fluid systems that exhibit multiscale behaviour, in particular, systems in which a Navier–Stokes model may not be valid in parts of the computational domain.
Reese, Jason M., Borg, Matthew K., Lockerby, Duncan A.   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Development of 6-way CFD-DEM-FEM momentum coupling interface using partitioned coupling approach

Results in Engineering
Fluid-particle-structure interactions (FPSI) govern a wide range of natural and engineering phenomena, from landslides to erosion in abrasive water jet cutting nozzles. Despite the importance of studying FPSI, existing numerical frameworks often simplify
Prasad Adhav, Xavier Besseron, Bernhard Peters   +2 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source