Results 31 to 40 of about 71,922 (264)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Vibroacoustic Modeling of Mechanically Coupled Structures: Artificial Spring Technique Applied to Light and Heavy Mediums

Shock and Vibration, 1996
This article deals with the modeling of vibrating structures immersed in both light and heavy fluids, and possible applications to noise control problems and industrial vessels containing fluids. A theoretical approach, using artificial spring systems to
L. Cheng
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Challenges of fully-coupled high-fidelity ditching simulations

MATEC Web of Conferences, 2018
An important element of the process of aircraft certification is the demonstration of the crashworthiness of the structure in the event of an emergency landing on water, also referred to as ditching.
Müller Maximilian, Woidt Malte, Haupt Matthias, Horst Peter   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Vibration characteristics of composite plates considering fluid-structure coupling

Advances in Mechanical Engineering
In order to investigate the influence of fluid-structure coupling on the dynamic characteristics of the amphibious aircraft, the free vibration characteristics of composite plates in contact with a bounded fluid are studied based on the combination of ...
Chen Wang, Qiang Liu
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Numerical Simulation of a Submerged Floating Tunnel: Validation and Analysis

Applied Sciences
The dynamic response analysis of submerged floating tunnels (SFTs) under seismic action is a complex two-way fluid–structure coupling problem that requires expertise in structural dynamics, fluid mechanics, and advanced computational methods. The coupled
Hao Li, Xiaohui Cheng, Hua Pan
doaj   +1 more source

Numerical simulation of air arc impinging to chamber shell with multi-physical coupling method of fluid-thermal-structure

AIP Advances, 2019
The air arc impinging to chamber shell during interruption current process were studied by experiments and numerical simulation. Firstly, strain characteristics of chamber shell were measured by the strain gauge, and the strain changing with times were ...
Yujie Wang, Lijun Wang, Shenli Jia
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source