Results 41 to 50 of about 71,922 (264)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fluid–structure interaction study of three-dimensional vehicle model under crosswind

open access: yesAdvances in Mechanical Engineering, 2015
It is very important to study fluid–structure interaction of vehicles which move in strong crosswind environment. For solving a fluid–structure interaction problem, the effect of the deformation and vibration of the elastic body on the flow field should ...
Hui Zhu, Yang Zhigang
doaj   +1 more source

Partitioned solver for strongly coupled fluid–structure interaction

open access: yesComputers & Fluids, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Habchi, Charbel   +7 more
openaire   +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Development of 6-way CFD-DEM-FEM momentum coupling interface using partitioned coupling approach

open access: yesResults in Engineering
Fluid-particle-structure interactions (FPSI) govern a wide range of natural and engineering phenomena, from landslides to erosion in abrasive water jet cutting nozzles. Despite the importance of studying FPSI, existing numerical frameworks often simplify
Prasad Adhav   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Flecs, a Flexible Coupling Shell Application to Fluid-Structure Interaction [PDF]

open access: yes, 2007
Numerical simulations involving multiple, physically different domains can be solved effectively by coupling simulation programs, or solvers. The coordination of the different solvers is commonly handled by a coupling shell. A coupling shell synchronizes the execution of the solvers and handles the transfer of data from one physical domain to another ...
M. Nool (Margreet)   +3 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Research Method of Wellbore Stability of Coal Formation in the Daniudi Gas Field

open access: yesShiyou jixie, 2015
Most studies on the coalbed wellbore stability are based on continuum mechanics,few research has involved fluid-structure coupling.The coal mechanical properties have been studied through the uniaxial and 3-axis compressive strength test of coal samples ...
Cheng Fushan   +5 more
doaj  

Dynamic Characteristics of Magnetorheological Mounted Metal Rubber Structures Under Multi-physics Coupling Conditions

open access: yesMedžiagotyra
To accurately predict the dynamic characteristics of MR mounting, the nonlinear electromagnetic coupling law between MR liquid and soft magnetic material and the solid-liquid interaction, the electromagnetic coupling and fluid-structure coupling ...
Bo PENG, Jintao SU, Jinquan NIE
doaj   +1 more source

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