Results 41 to 50 of about 389,612 (284)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Vibroacoustic Modeling of Mechanically Coupled Structures: Artificial Spring Technique Applied to Light and Heavy Mediums

Shock and Vibration, 1996
This article deals with the modeling of vibrating structures immersed in both light and heavy fluids, and possible applications to noise control problems and industrial vessels containing fluids. A theoretical approach, using artificial spring systems to
L. Cheng
doaj   +1 more source

A smoothed particle hydrodynamics solver for hydroelastic interactions between fluid and structure [PDF]

AIP Advances
There is still a lack of accurate and stable numerical solvers for Fluid–Structure Interaction (FSI) problems involving violent fluid flows and large deformations of structures.
Takafumi Gotoh, Abbas Khayyer, Dongfang Liang, Hitoshi Gotoh   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

One-loop quantum corrections to cosmological scalar field potentials

, 2007
We study the loop corrections to potentials of complex or coupled real scalar fields used in cosmology to account for dark energy, dark matter or dark fluid.
Alexandre Arbey, Farvah Mahmoudi, M. E. Peskin, T.-P. Cheng   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Vibration characteristics of composite plates considering fluid-structure coupling

Advances in Mechanical Engineering
In order to investigate the influence of fluid-structure coupling on the dynamic characteristics of the amphibious aircraft, the free vibration characteristics of composite plates in contact with a bounded fluid are studied based on the combination of ...
Chen Wang, Qiang Liu
doaj   +1 more source

Challenges of fully-coupled high-fidelity ditching simulations

MATEC Web of Conferences, 2018
An important element of the process of aircraft certification is the demonstration of the crashworthiness of the structure in the event of an emergency landing on water, also referred to as ditching.
Müller Maximilian, Woidt Malte, Haupt Matthias, Horst Peter   +3 more
doaj   +1 more source

Computational evaluation of flight performance of flapping-wing nano air vehicles using hierarchical coupling of nonlinear dynamic and fluid-structure interaction analyses

Engineering Applications of Computational Fluid Mechanics, 2023
This study endeavours to introduce an inventive hierarchical coupling methodology for evaluating the flight capabilities of polymer micromachined flapping-wing nano air vehicles (FWNAVs) using advanced computational tools.
Rashmikant, M. Onishi, K. Sugikawa, D. Ishihara   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source