Results 211 to 220 of about 4,388,444 (360)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Structural controls on multi-field coupled ore-bearing hydrothermal migration in Zhugongtang Zn-Pb deposit, Southwestern China. [PDF]

Sci Rep
Zhang Y, Zhou W, Zhang W, Zhang J, Tang C.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The Brief Case: Knee joint infection caused by <i>Neisseria mucosa</i>. [PDF]

J Clin Microbiol
Zheng C, Song M, Guo Y, Hao J, Liu S, Ye J, Gao W, Zhang H, Feng Z, Zuo H, Zhao Z, Zhang L.   +11 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Micro- and Nanoscale Flow Mechanisms in Shale Oil: A Fluid-Solid Coupling Model Integrating Adsorption, Slip, and Stress Sensitivity. [PDF]

Nanomaterials (Basel)
Liu Z, Yi Z, Sheng G, Lu G, Xing X, Zhang X.   +5 more
europepmc   +1 more source

Rosmarinic Acid as A Flavonoids Ameliorated Cytokines and Oxidative Stress Biomarkers in the Lung Lavage Fluid of Rats [PDF]

Vahideh Sadat Abbasnia, Mohsen Foadoddini, Mohammad Reza Khazdair   +2 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Analysis of Off-Design Performance and Thermal-Fluid-Structural Coupling Characteristics of an Adjustable Air Ejector. [PDF]

Materials (Basel)
Zhang Y, Yan L, Zhang J, Ma S, Guo W.
europepmc   +1 more source