Results 61 to 70 of about 54,370 (265)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On the power of (even a little) resource pooling

open access: yesStochastic Systems, 2012
We propose and analyze a multi-server model that captures a performance trade-off between centralized and distributed processing. In our model,a fraction p of an available resource is deployed in a centralized manner (e.g., to serve a most-loaded station)
Kuang Xu, John N. Tsitsiklis
doaj  

Assessment of fluid neutral models for a detached ITER case

open access: yesNuclear Materials and Energy, 2017
We compare the plasma sources (particle, parallel momentum and ion energy) due to plasma-neutral interactions computed with different fluid neutral models with the sources from a Monte Carlo simulation of the kinetic neutral equation.
N. Horsten   +3 more
doaj   +1 more source

Transient generalized Taylor-Couette flow: a semi-analytical approach

open access: yesJournal of Taibah University for Science, 2020
Semi-analytical solution of transient generalized Taylor-Couette flow of a viscous, incompressible fluid between the gaps of concentric rotating cylinders under applied azimuthal pressure gradient ispresented.
Basant Kumar Jha, Yahaya Jibrin Danjuma
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Computational fluid dynamics-based hull form optimization using approximation method

open access: yesEngineering Applications of Computational Fluid Mechanics, 2018
With the rapid development of the computational technology, computational fluid dynamics (CFD) tools have been widely used to evaluate the ship hydrodynamic performances in the hull forms optimization.
Shenglong Zhang   +4 more
doaj   +1 more source

Numerical investigation of the flow of a micropolar fluid through a porous channel with expanding or contracting walls

open access: yesPropulsion and Power Research, 2014
In this paper, we study the flow of a micropolar fluid in a porous channel with expanding or contracting walls. First, we use spectral collocation method on the governing equations to obtain an initial approximation for the solution of equations.
M.T. Darvishi   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Thermal Convective Instabilities and Chaos in a Rotating Hybrid Nanofluid Layer with Cattaneo–Christov Heat Flux Model

open access: yesComplexity, 2022
The linear and nonlinear dynamics of thermal convection of a rotating hybrid nanofluid layer heated from below with the Cattaneo–Christov heat flux model are studied in this paper. Starting from the flow equations of a hybrid nanofluid and exploiting the
Sèmako Justin Dèdèwanou   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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