Results 51 to 60 of about 53,841 (265)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

On the power of (even a little) resource pooling

open access: yesStochastic Systems, 2012
We propose and analyze a multi-server model that captures a performance trade-off between centralized and distributed processing. In our model,a fraction p of an available resource is deployed in a centralized manner (e.g., to serve a most-loaded station)
Kuang Xu, John N. Tsitsiklis
doaj  

Transient generalized Taylor-Couette flow: a semi-analytical approach

open access: yesJournal of Taibah University for Science, 2020
Semi-analytical solution of transient generalized Taylor-Couette flow of a viscous, incompressible fluid between the gaps of concentric rotating cylinders under applied azimuthal pressure gradient ispresented.
Basant Kumar Jha, Yahaya Jibrin Danjuma
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Computational fluid dynamics-based hull form optimization using approximation method

open access: yesEngineering Applications of Computational Fluid Mechanics, 2018
With the rapid development of the computational technology, computational fluid dynamics (CFD) tools have been widely used to evaluate the ship hydrodynamic performances in the hull forms optimization.
Shenglong Zhang   +4 more
doaj   +1 more source

Lubrication Approximation for Fluids with Shear-Dependent Viscosity [PDF]

open access: yesFluids, 2019
We present dimensionally reduced Reynolds type equations for steady lubricating flows of incompressible non-Newtonian fluids with shear-dependent viscosity by employing a rigorous perturbation analysis on the governing equations of motion. Our analysis shows that, depending on the strength of the power-law character of the fluid, the novel equation can
Pereira, Bruno M. M.   +4 more
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Assessment of fluid neutral models for a detached ITER case

open access: yesNuclear Materials and Energy, 2017
We compare the plasma sources (particle, parallel momentum and ion energy) due to plasma-neutral interactions computed with different fluid neutral models with the sources from a Monte Carlo simulation of the kinetic neutral equation.
N. Horsten   +3 more
doaj   +1 more source

Natural convection flow near a vertical plate that applies a shear stress to a viscous fluid. [PDF]

open access: yesPLoS ONE, 2013
The unsteady natural convection flow of an incompressible viscous fluid near a vertical plate that applies an arbitrary shear stress to the fluid is studied using the Laplace transform technique. The fluid flow is due to both the shear and the heating of
Qammar Rubbab   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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