Results 71 to 80 of about 4,601,994 (298)

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

The initial flow dynamics of light atoms through carbon nanotubes [PDF]

, 2011
Carbon nanotubes are becoming increasingly viable as membranes for application in a wide variety of nano-fluidic applications, such as nano-scale nozzles.
Kim, Daejoong, Daejoong Kim, Cannon, James, Ortwin Hess, James Cannon, Hess, Ortwin   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Photoacclimation and Photoadaptation Sensitivity in a Global Ocean Ecosystem Model

Journal of Advances in Modeling Earth Systems
Chlorophyll underpins ocean productivity yet simulating chlorophyll across biomes, seasons and depths remains challenging for earth system models. Inconsistencies are often attributed to misrepresentation of the myriad nutrient supply, growth and loss ...
Charles A. Stock, John P. Dunne, Jessica Y. Luo, Andrew C. Ross, Nicolas VanOostende, Niki Zadeh, Theresa J. Cordero, Xiao Liu, Yi‐Cheng Teng   +8 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Exploring multiyear-to-decadal North Atlantic sea level predictability and prediction using machine learning

npj Climate and Atmospheric Science
Coastal communities face substantial risks from long-term sea level rise and decadal sea level variations, with the North Atlantic and U.S. East Coast being particularly vulnerable under changing climates. Employing a self-organizing map-based framework,
Qinxue Gu, Liping Zhang, Liwei Jia, Thomas L. Delworth, Xiaosong Yang, Fanrong Zeng, William F. Cooke, Shouwei Li   +7 more
doaj   +1 more source

Large eddy simulations of methane oxidation at ultra-wet conditions in a model gas turbine combustor applying detailed chemistry

Journal of Fluid Science and Technology, 2014
The addition of steam to the combustion process is a promising avenue, in order to reduce harmful emissions and simultaneously increase the efficiency. In contrast to traditional flames where the heat release exhibits a thin flame front, operating under ...
Oliver KRÜGER, Christophe DUWIG, Steffen TERHAAR, Christian Oliver PASCHEREIT   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Handbook of mathematical fluid dynamics.

, 2004
The Handbook of Mathematical Fluid Dynamics is a compendium of essays that provides a survey of the major topics in the subject. Each article traces developments, surveys the results of the past decade, discusses the current state of knowledge and ...
Friedlander, Susan, Serre, D.(Denis)
core  

The dynamics of quantum fluids

We review experimental and theoretical progress in the physical description of the dynamics of the quantum fluids \he4 and \he3. Historically, the elementary excitations in these systems have been identified as phonons and rotons and, in \he3, collective zero sound and spin-fluctuations.
Godfrin, Henri, Krotscheck, Eckhard
openaire   +3 more sources