Results 51 to 60 of about 242,124 (267)

Flow-dependent fluorescence of CCVJ

open access: yesJournal of Biological Engineering, 2017
Background The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a previously reported photoisomeric
Markus J. Schmidt   +2 more
doaj   +1 more source

Caging Dynamics in a Granular Fluid [PDF]

open access: yesPhysical Review Letters, 2007
We report an experimental investigation of the caging motion in a uniformly heated granular fluid, for a wide range of filling fractions, $ϕ$. At low $ϕ$ the classic diffusive behavior of a fluid is observed. However, as $ϕ$ is increased, temporary cages develop and particles become increasingly trapped by their neighbors.
Reis, Pedro M.   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Quantifying Equilibrium Climate Sensitivity to Atmospheric Chemistry and Composition Representations in GFDL‐CM4.0 and GFDL‐ESM4.1

open access: yesGeophysical Research Letters
Equilibrium climate sensitivity (ECS) quantifies surface warming in response to doubled pre‐industrial CO2 (2xCO2). Uncertainty in estimates arises from diverse model representations and climate‐chemistry feedbacks.
L. T. Sentman   +6 more
doaj   +1 more source

On the Flight Control of Flapping Wing Micro Air Vehicles with Model-Based Reinforcement Learning

open access: yesProceedings
Hummingbirds and insects can hover in disturbed conditions, escape from predators with a very fast response, fly for miles without landing, etc [...]
Romain Poletti   +2 more
doaj   +1 more source

Recent increases in tropical cyclone intensification rates

open access: yesNature Communications, 2019
Tropical cyclones that rapidly intensify are associated with the highest forecast errors and the strongest storms. This study shows that the proportion of tropical cyclones that rapidly intensify recently increased in the Atlantic basin, and that this ...
Kieran T. Bhatia   +6 more
doaj   +1 more source

Dynamics of fluid mixtures in nanospaces [PDF]

open access: yesThe Journal of Chemical Physics, 2011
A multicomponent extension of our recent theory of simple fluids [U. M. B. Marconi and S. Melchionna, J. Chem. Phys. 131, 014105 (2009)] is proposed to describe miscible and immiscible liquid mixtures under inhomogeneous, nonsteady conditions typical of confined fluid flows.
Marconi Umberto Marini Bettolo   +2 more
openaire   +5 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

On the Utility of the Transient Climate Response

open access: yesGeophysical Research Letters
The Transient Climate Response (TCR) is a metric of climate sensitivity relevant to present‐day climate change, but has been less studied than the Equilibrium Climate Sensitivity.
Nadir Jeevanjee   +4 more
doaj   +1 more source

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