Results 51 to 60 of about 1,253,068 (289)

Computational Fluid Dynamics Analysis Into the Improvement of Seakeeping Characteristics of a Fast Craft Using AXE-Bow [PDF]

, 2015
It is obviously understood that hull shape affects the movement characteristics and operability of a ship. There are several ways which can be conducted in order to improve the operability of a ship one of those is by improving ship bow.
Li, B. (Binbin), Romadhoni, R. (Romadhoni), Utama, I. (IKAP)   +2 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

GFDL's SPEAR Seasonal Prediction System: Initialization and Ocean Tendency Adjustment (OTA) for Coupled Model Predictions

Journal of Advances in Modeling Earth Systems, 2020
The next‐generation seasonal prediction system is built as part of the Seamless System for Prediction and EArth System Research (SPEAR) at the Geophysical Fluid Dynamics Laboratory (GFDL) of the National Oceanic and Atmospheric Administration (NOAA ...
Feiyu Lu, Matthew J. Harrison, Anthony Rosati, Thomas L. Delworth, Xiaosong Yang, William F. Cooke, Liwei Jia, Colleen McHugh, Nathaniel C. Johnson, Mitchell Bushuk, Yongfei Zhang, Alistair Adcroft   +11 more
doaj   +1 more source

Liquid oil painting: Free and forced convection in an enclosure with mechanical and thermal forcing [PDF]

, 2012
A fluid dynamics video is linked to this article, which have been submitted to the Gallery of Fluid Motion as part of the 65th American Physical Society meeting of the Division of Fluid Dynamics, held in San Diego, California, USA, over 17-20 November ...
King, Martin P., Sheard, Gregory J., Wong, Kean Y.   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Characterising Fatigue Behaviour of Nodular Cast Iron Using Micromechanical Simulations [PDF]

MATEC Web of Conferences, 2019
Elastic-plastic porous materials experience an increase in the mean void volume fraction when they are subjected to cyclic loading. This behavior is known both from the experiments and simulations in the literature.
Lukhi Mehul, Kuna Meinhard, Hütter Geralf   +2 more
doaj   +1 more source

Euler's fluid equations: Optimal Control vs Optimization

, 2009
An optimization method used in image-processing (metamorphosis) is found to imply Euler's equations for incompressible flow of an inviscid fluid, without requiring that the Lagrangian particle labels exactly follow the flow lines of the Eulerian velocity
Agrachev, Agrachev, Arnold, Bloch, Bloch, Bloch, Bloch, Constantin, Darryl D. Holm, Holm, Holm, Kuz'min, Lamb, Majda, Manakov, Marsden, Monaghan, Olver, Osledets, Ratiu, Russo, Trouvé   +21 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Explicit Prediction of Continental Convection in a Skillful Variable‐Resolution Global Model

Journal of Advances in Modeling Earth Systems, 2019
We present a new global‐to‐regional model, cfvGFS, able to explicitly (without parameterization) represent convection over part of the Earth. This model couples the Geophysical Fluid Dynamics Laboratory Finite‐Volume Cubed‐Sphere Dynamical Core (FV3) to ...
Lucas M. Harris, Shannon L. Rees, Matthew Morin, Linjiong Zhou, William F. Stern   +4 more
doaj   +1 more source