Results 51 to 60 of about 383,488 (316)

Fluid–particle dynamics in canalithiasis [PDF]

Journal of The Royal Society Interface, 2008
The semicircular canals (SCCs; located in the inner ear) are the primary sensors for angular motion. Angular head movements induce a fluid flow in the SCCs. This flow is detected by afferent hair cells inside the SCCs. Canalithiasis is a condition where small particles disturb this flow, which leads to benign paroxysmal positional vertigo (top-shelf ...
Obrist, D, Hegemann, S
openaire   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Skillful seasonal prediction of wind energy resources in the contiguous United States

Communications Earth & Environment
A key challenge with the wind energy utilization is that winds, and thus wind power, are highly variable on seasonal to interannual timescales because of atmospheric variability.
Xiaosong Yang, Thomas L. Delworth, Liwei Jia, Nathaniel C. Johnson, Feiyu Lu, Colleen McHugh   +5 more
doaj   +1 more source

Fluid Dynamics of Bacterial Turbulence [PDF]

Physical Review Letters, 2013
Self-sustained turbulent structures have been observed in a wide range of living fluids, yet no quantitative theory exists to explain their properties. We report experiments on active turbulence in highly concentrated 3D suspensions of Bacillus subtilis and compare them with a minimal fourth-order vector-field theory for incompressible bacterial ...
Dunkel, Jörn, Heidenreich, Sebastian, Drescher, Knut, Wensink, Henricus H., Bär, Markus, Goldstein, Raymond E.   +5 more
openaire   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Superconfinement tailors fluid flow at microscales.

, 2015
Understanding fluid dynamics under extreme confinement, where device and intrinsic fluid length scales become comparable, is essential to successfully develop the coming generations of fluidic devices.
Aarts, Dirk G., Pagonabarraga, Ignacio, Setu, Siti A., Hernández-Machado, A, Ledesma-Aguilar, Rodrigo, Setu, Siti Aminah, Aarts, Dirk, Hernández-Machado, Aurora, Dullens, Roel P.A., Ledesma-Aguilar, R, Pagonabarraga, I, Dullens, Roel, Dullens, Roel P. A., Setu, SA, Dullens, RPA, Aarts, DG, Aarts, Dirk G. A. L.   +16 more
core   +1 more source

Flow-dependent fluorescence of CCVJ

Journal of Biological Engineering, 2017
Background The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a previously reported photoisomeric
Markus J. Schmidt, David Sauter, Thomas Rösgen   +2 more
doaj   +1 more source

Caging Dynamics in a Granular Fluid [PDF]

Physical Review Letters, 2007
We report an experimental investigation of the caging motion in a uniformly heated granular fluid, for a wide range of filling fractions, $ϕ$. At low $ϕ$ the classic diffusive behavior of a fluid is observed. However, as $ϕ$ is increased, temporary cages develop and particles become increasingly trapped by their neighbors.
Reis, Pedro M., Ingale, Rohit A., Shattuck, Mark D.   +2 more
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

GFDL's SPEAR Seasonal Prediction System: Initialization and Ocean Tendency Adjustment (OTA) for Coupled Model Predictions

Journal of Advances in Modeling Earth Systems, 2020
The next‐generation seasonal prediction system is built as part of the Seamless System for Prediction and EArth System Research (SPEAR) at the Geophysical Fluid Dynamics Laboratory (GFDL) of the National Oceanic and Atmospheric Administration (NOAA ...
Feiyu Lu, Matthew J. Harrison, Anthony Rosati, Thomas L. Delworth, Xiaosong Yang, William F. Cooke, Liwei Jia, Colleen McHugh, Nathaniel C. Johnson, Mitchell Bushuk, Yongfei Zhang, Alistair Adcroft   +11 more
doaj   +1 more source