Results 41 to 50 of about 4,601,994 (298)

Prospects for a prolonged slowdown in global warming in the early 21st century

Nature Communications, 2016
Rates of global mean surface temperature increases have recently slowed. Here, using climate models, Knutson et al. examine how internal variability influences temperature evolution, finding that the recent slowdown may persist if coincident with an ...
Thomas R. Knutson, Rong Zhang, Larry W. Horowitz   +2 more
doaj   +1 more source

Adjoint-based shape optimization for the minimization of flow-induced hemolysis in biomedical applications

Engineering Applications of Computational Fluid Mechanics, 2021
This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in blood flows through biomedical devices.Despite the significant progress in relevant experimental studies, the ever ...
Georgios Bletsos, Niklas Kühl, Thomas Rung   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Fluid–particle dynamics in canalithiasis [PDF]

Journal of The Royal Society Interface, 2008
The semicircular canals (SCCs; located in the inner ear) are the primary sensors for angular motion. Angular head movements induce a fluid flow in the SCCs. This flow is detected by afferent hair cells inside the SCCs. Canalithiasis is a condition where small particles disturb this flow, which leads to benign paroxysmal positional vertigo (top-shelf ...
Obrist, D, Hegemann, S
openaire   +4 more sources

Development and commissioning of an aeroacoustic test bench for the investigation of single and coaxial propeller noise

Acta Acustica
This paper describes the design and commissioning of an aeroacoustic test rig for the study of single and coaxial propeller propulsive systems. The size of the propellers matches typical drone applications.
Gallo Erica, De Decker Julien, Bresciani Andrea, Haezebrouck Pauline, Garone Emanuele, Schram Christophe   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Fluid Dynamics of Bacterial Turbulence [PDF]

Physical Review Letters, 2013
Self-sustained turbulent structures have been observed in a wide range of living fluids, yet no quantitative theory exists to explain their properties. We report experiments on active turbulence in highly concentrated 3D suspensions of Bacillus subtilis and compare them with a minimal fourth-order vector-field theory for incompressible bacterial ...
Dunkel, Jörn, Heidenreich, Sebastian, Drescher, Knut, Wensink, Henricus H., Bär, Markus, Goldstein, Raymond E.   +5 more
openaire   +4 more sources

Author Correction: Recent increases in tropical cyclone intensification rates

Nature Communications, 2019
The original version of this Article contained an error in the second sentence of the first paragraph of the ‘Quantile mapping’ section of the Methods, which incorrectly read ‘We primarily focus on results produced using an additive version of QDM26 by ...
Kieran T. Bhatia, Gabriel A. Vecchi, Thomas R. Knutson, Hiroyuki Murakami, James Kossin, Keith W. Dixon, Carolyn E. Whitlock   +6 more
doaj   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Numerical simulations of complex fluid-fluid interface dynamics [PDF]

, 2013
Interfaces between two fluids are ubiquitous and of special importance for industrial applications, e.g., stabilisation of emulsions. The dynamics of fluid-fluid interfaces is difficult to study because these interfaces are usually deformable and their ...
Harting, J.D.R., Frijters, S., T. Krüger, J. Harting, Krueger, Timm, F. Günther, B. Kaoui, Krüger, T., Günther, F., S. Frijters, Harting, J., Günther, F.S., Kaoui, B., Frijters, S.C.J.   +13 more
core   +1 more source