Results 61 to 70 of about 2,038,662 (294)
Explicit equations for leak rates through narrow cracks
, 2005 Explicit equations to describe the leak rate of a single phase fluid through a narrow crack under a low pressure gradient have been developed and are presented.
Bagshaw, N.M., Beck, S.B.M., Yates, J.R.
core +1 more source
Three-dimensional flow of Newtonian and Boger fluids in square-square contractions [PDF]
, 2009 The flow of a Newtonian fluid and a Boger fluid through sudden square–square contractions was investigated experimentally aiming to characterize the flow and provide quantitative data for benchmarking in a complex three-dimensional flow.
Alves, M.A. +3 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Variable Size Twin-Rotor Wind Turbine
Energies, 2019 The paper presents a new concept of a vertical axis wind turbine. The idea is focused on small wind turbines, and therefore, the dominating quality is safety. Another important necessary feature is efficient operation at small winds.
Piotr Doerffer +3 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
LARGE-EDDY SIMULATIONS OF PARTICLE-LADEN TURBULENT JETS
TASK Quarterly, 2012 The work presents an application of Large-Eddy Simulation (LES) for turbulent two-phase flows with dispersed particles. For the simulations of the continuous phase (fluid), an academic, finite volume LES solver was applied and customised. For comparison
MIROSŁAW ŁUNIEWSKI +2 more
doaj
, 1978 A valve assembly is reported for controlling the flow of fluids between the inlet and outlet of a fluid valve. The valve assembly contains a barrier element which is porous for providing fluid communication between the valve inlet and outlet.
Huber, W. C.
core +1 more source
Dissipative hydrodynamics in 2+1 dimension
, 2006 In 2+1 dimension, we have simulated the hydrodynamic evolution of QGP fluid with dissipation due to shear viscosity. Comparison of evolution of ideal and viscous fluid, both initialised under the same conditions e.g.
A. K. Chaudhuri +4 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source