Results 71 to 80 of about 2,052,592 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MODERNISATION OF STEAM TURBINE CONSTRUCTION AT REGENERATIVE STEAM EXTRACTION POINT

TASK Quarterly, 2010
The paper presents a methodology which has led to improvement of the turbine stage performance in the regenerative steam extraction chamber area by introducing a ring which collects the leakage flow from the gaps over unshrouded rotor blade tips and ...
MARIUSZ SZYMANIAK, ANDRZEJ GARDZILEWICZ
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

NUMERICAL SIMULATION OF MODEL HELICOPTER ROTOR IN HOVER

TASK Quarterly, 2008
The article presents details of a URANS simulation of the flow field near a hovering model of the Caradonna and Tung (1981) helicopter rotor [1]. The CFD code SPARC [2] proves to be capable of capturing the aerodynamics of a two -bladed rotor in high ...
PIOTR DOERFFER, OSKAR SZULC
doaj  

BI-AXIAL NEUTRAL AXIS TRACKING FOR CRACK DETECTION IN WIND TURBINE TOWERS

TASK Quarterly, 2015
This work concentrates on Structural Health Monitoring (SHM) of a wind turbine tower. The paper investigates the use of a decision level data fusion based on bi-axial tracking of change in the neutral axis (NA) position for damage detection in wind ...
ROHAN SOMAN, PAWEL MALINOWSKI, WIESLAW OSTACHOWICZ   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Two-dimensional numerical simulation of the behavior of a circular capsule subject to an inclined centrifugal force near a plate in a fluid

Journal of Fluid Science and Technology, 2017
In order to examine mechanical interactions between erythrocytes and a blood vessel surface, the frictional characteristics between erythrocytes and plates in plasma have been measured by an inclined centrifuge microscope.
Suguru MIYAUCHI, Toshiyuki HAYASE, Arash Alizad BANAEI, Jean-Christophe LOISEAU, Luca BRANDT, Fredrik LUNDELL   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

HOLE EXTENSION EFFECT ON TRANSPIRATION FLOW EFFICIENCY

TASK Quarterly, 2015
The present analysis of the hole extension effect on the transpiration flow efficiency is a part of the research [1] which aims at defining a physical transpiration model of the flow through perforated plates.
TOMASZ LEWANDOWSKI, PIOTR DOERFFER
doaj   +1 more source