Results 81 to 90 of about 1,118,588 (301)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

SIMULATION OF FLUID-STRUCTURE INTERACTIONBASED ON AN IMMERSED-SOLID METHOD [PDF]

Journal of Mechanical Engineering and Sciences, 2013
A new method for studying the interaction between an elastic object and a fluid has been developed. The fluid phase including solid interface is solved by our immersed solid method of body-force type.
Takeo Kajishima , Shintaro Takeuchi
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Performance prediction of air drag brake units for Shinkansen and verification by running test

Nihon Kikai Gakkai ronbunshu
The performance of Air Drag Brake (ADB) units for Shinkansen trains was predicted using wind tunnel experiments and numerical analysis, and running tests were carried out using a test car equipped with a number of ADB units.
Hajime TAKAMI, Yuto ARAKI, Masanobu IIDA, Takumi ABE, Yoshiki KIKUCHI, Akihito KIMURA   +5 more
doaj   +1 more source

Simple prediction method of unstable fluid force in turbine blade row of steam turbine

Nihon Kikai Gakkai ronbunshu, 2016
Unstable fluid force may be induced by rotor blade eccentricity in turbo machinery such as steam turbines. To develop a prediction method for unstable fluid force in turbine blade rows, we calculated the fluid force by using computational fluid dynamics (
Kiyoshi YABATA, Kazuyuki YAMAGUCHI, Kenichi MURATA   +2 more
doaj   +1 more source

Spreading of Fluids on Solids Under Pressure: Effect of Slip [PDF]

, 2010
Spreading of different types of fluid on substrates under an impressed force is an interesting problem. Here we study spreading of four fluids, having different hydrophilicity and viscosity on two substrates - glass and perspex, under an external force ...
Dutta, Tapati, Nag, Soma, Tarafdar, Sujata   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Effects of Fluid Velocity Gradients on Heavy Quark Energy Loss [PDF]

, 2013
We use holographic duality to analyze the drag force on, and consequent energy loss of, a heavy quark moving through a strongly coupled conformal fluid with non-vanishing gradients in its velocity and temperature. We derive the general expression for the
Lekaveckas, Mindaugas, Rajagopal, Krishna   +1 more
core   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Design and Simulation of Small-Scale Horizontal-Axis Wind Turbine with Diffuser Effect

MATEC Web of Conferences, 2019
The article presents the results of the investigation of a rotor assembly of a wind turbine with a horizontal axis of rotation. The rotor is equipped with a diffuser which is an integral part of the power generating unit.
Czyż Zbigniew, Karpiński Paweł, Klepka Tomasz, Szkoda Zbigniew   +3 more
doaj   +1 more source