Results 61 to 70 of about 335,525 (308)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

THE EFFECT OF N-NH3 INCLUSION ON THE DEGRADATION OF TANNIN OF SORGHUM GRAIN BY RUMEN MICROBES [PDF]

open access: yes, 2010
Two experiments were conducted to study the effect of N-NH3 inclusion in the rumen liquor on the degradation of tannin of whole sorghum grain. The first experiment was carried out to determine the effect of N-NH3 inclusion doses in the rumen liquor on ...
Achmadi, Joelal
core  

Table C.3: Fluid inclusion data of H2O-salt inclusions from light rock types of the Petermannketten

open access: yes, 2002
Table C.3: Fluid inclusion data of H2O-salt inclusions from light rock types of the ...
Kleinefeld, Bärbel   +1 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Geology, alteration, mineralization, Geochemistry, fluid inclusion, petrology, petrogenises and U-Pb zircon dating of diorite dykes in the Robaie copper area (South of Damghan)

open access: yesJournal of Economic Geology, 2020
Introduction The Robaie copper area is located 95 kilometers South of Damghan in the Semnan province. The study area has coordinates between 54˚30΄37˝to 54˚30΄42.71˝ latitude and 35˚22΄29.41˝ to 35˚23΄47.54˝ longitude. Geotectonically, the study area is
Mehdi Mahdavi Akerdi   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Hydrothermal Fluid evolution in the Dalli porphyry Cu-Au Deposit: Fluid Inclusion microthermometry studies

open access: yesJournal of Economic Geology, 2015
Introduction A wide variety of world-class porphyry Cu deposits occur in the Urumieh-Dohktar magmatic arc (UDMA) of Iran.The arc is composed of calc-alkaline granitoid rocks, and the ore-hosting porphyry intrusions are dominantly granodiorite to quartz ...
Alireza Zarasvandi   +4 more
doaj  

Hydrocarbon charge history of deeply buried clastic reservoirs in the Bozi area of the Kuqa Depression, western China: implications for deep and ultra-deep petroleum exploration

open access: yesFrontiers in Earth Science
Significant progress has recently been made in deep and ultra-deep oil and gas exploration globally, demonstrating enormous exploration potential of the deep and ultra-deep strata. However, the accumulation and preservation pattern of deep and ultra-deep
Peng Yang   +11 more
doaj   +1 more source

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