Results 61 to 70 of about 2,739,725 (241)

Mineralization and Fluid Inclusion Studies in the Tarz Carbonate-Hosted Pb-Zn Deposit, Central Iran

open access: yesJournal of Economic Geology, 2019
Introduction More than 300 sediment-hosted Zn–Pb deposits and occurrences have been recognized in Iran (Rajabi et al., 2013). Most of these deposits are concentrated in the Central Alborz, Tabas-Posht-e-Badam, Malayer-Esfahan and Yazd-Anarak ...
Balandeh Aminzadeh
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Fluid Evolution During Mineralization of Atashkuh Fluorite-Barite (±Sulfide) Deposit, South of Delijan

open access: yesJournal of Economic Geology, 2016
Introduction More than 30 fluorite occurrences with approximately 1.35 million tons of reserves have been recognized in Iran (Ghorbani, 2013). The Atashkuh fluorite-barite (±sulfide) deposit is one of four occurrences located south of the city of ...
Seyed Javad Moghaddasi   +2 more
doaj  

Formation and evolution stages of gold rich Barika massive sulfide deposit, east of Sardasht, northern Sanandaj-Sirjan zone: based on structural, textural and fluid inclusion studies

open access: yesJournal of Economic Geology, 2010
Barika gold (and silver) rich massive sulfide deposit is located 18 km east of Sardasht, north western part of Sanandaj-Sirjan metamorphic zone. Rock units outcropped in this area are Cretaceous metamorphosed volcano-sedimentary rocks in green schist ...
Hossein Ali Tajeddin   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ore genesis of the Chazangcuo Cu-Pb-Zn deposit in Tibet: evidence from mineralogy, fluid inclusions, S-Pb isotopes, and elemental geochemistry

open access: yesFrontiers in Earth Science
The Chazangcuo copper-lead-zinc deposit (hereafter referred to as the Chazangcuo deposit) is situated in the northern portion of the western section of the Gangdese polymetallic metallogenic belt in Tibet, with ore bodies strictly governed by Linzizong ...
Yan Li   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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