Results 61 to 70 of about 335,525 (308)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
THE EFFECT OF N-NH3 INCLUSION ON THE DEGRADATION OF TANNIN OF SORGHUM GRAIN BY RUMEN MICROBES [PDF]
Two experiments were conducted to study the effect of N-NH3 inclusion in the rumen liquor on the degradation of tannin of whole sorghum grain. The first experiment was carried out to determine the effect of N-NH3 inclusion doses in the rumen liquor on ...
Achmadi, Joelal
core
Table C.3: Fluid inclusion data of H2O-salt inclusions from light rock types of the Petermannketten
Table C.3: Fluid inclusion data of H2O-salt inclusions from light rock types of the ...
Kleinefeld, Bärbel +1 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Introduction The Robaie copper area is located 95 kilometers South of Damghan in the Semnan province. The study area has coordinates between 54˚30΄37˝to 54˚30΄42.71˝ latitude and 35˚22΄29.41˝ to 35˚23΄47.54˝ longitude. Geotectonically, the study area is
Mehdi Mahdavi Akerdi +3 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Introduction A wide variety of world-class porphyry Cu deposits occur in the Urumieh-Dohktar magmatic arc (UDMA) of Iran.The arc is composed of calc-alkaline granitoid rocks, and the ore-hosting porphyry intrusions are dominantly granodiorite to quartz ...
Alireza Zarasvandi +4 more
doaj
Significant progress has recently been made in deep and ultra-deep oil and gas exploration globally, demonstrating enormous exploration potential of the deep and ultra-deep strata. However, the accumulation and preservation pattern of deep and ultra-deep
Peng Yang +11 more
doaj +1 more source

