Results 71 to 80 of about 335,525 (308)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Convective instability of a spherical fluid inclusion
When a vertical temperature gradient is applied to a large solid containing a spherical fluid inclusion, the temperature in the fluid is a function only of height.
Yih, Chia‐shun, Chia-Shun Yih
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The aim of this study is to provide the first detailed mineralogical and fluid-inc1usion description of emeralds from the Delbegetey deposit (Kazakhstan).
Gavrilenko, Egor +3 more
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
منطقه اکتشافي دهسلم در خراسان جنوبي و در کمربند آتشفشاني – نفوذي بلوک لوت قرار گرفته است. تودههاي نيمه عميق حدواسط تا اسيدي مربوط به اليگوسن، درون تواليهاي آتشفشاني، ماسهسنگ و سيلتستون ائوسن نفوذ کردهاند.
Karimpour, M. H. +5 more
core
Mineralization and Fluid Inclusion Studies in the Tarz Carbonate-Hosted Pb-Zn Deposit, Central Iran
Introduction More than 300 sediment-hosted Zn–Pb deposits and occurrences have been recognized in Iran (Rajabi et al., 2013). Most of these deposits are concentrated in the Central Alborz, Tabas-Posht-e-Badam, Malayer-Esfahan and Yazd-Anarak ...
Balandeh Aminzadeh
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

