Results 71 to 80 of about 321,488 (263)

Episodes of fissure formation in the Alps: connecting quartz fluid inclusion, fissure monazite age, and fissure orientation data. [PDF]

Swiss J Geosci, 2021
Gnos E, Mullis J, Ricchi E, Bergemann CA, Janots E, Berger A.   +5 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Fluid inclusion and C-H-O-S-Pb isotope characteristics and geological significance of lead-zinc-fluorite deposits in the Geleche area, Laifeng, Hubei Province

地质科技通报
Objective Lead-zinc mineralization is widely distributed in southwestern Hubei Province, but no large deposits have been found thus far, and there is a lack of systematic studies on metallogenic systems.
Hua LUO, Pan GUO, Li LIU, Longke PAN, Xianfeng DUAN, Qixi MAO, Mingfang LIAO   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Laser-Raman Analysis of Individual Fluid Inclusions and Hydrocarbon-Fluid Evolution in the Marine–Terrestrial Transitional Longtan Formation Shale, Southern Sichuan Basin

Applied Sciences
This study integrates microthermometry and laser-Raman spectroscopy of individual fluid inclusions with basin modelling to reconstruct the hydrocarbon-fluid evolution and multistage re-mobilisation of the Permian Longtan Formation transitional marine ...
Longyi Wang, Xizhe Li, Ya’na Chen, Nijun Qi, Wenxuan Yu, Yuchuan Chen, Sijie He, Yuhang Zhou, Yaqi Zhao, Jing Xiang   +9 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Differential enrichment process of shale gas in Cambrian Qiongzhusi Formation in middle section of Deyang-Anyue rift trough, Sichuan Basin: evidence from fracture veins and fluid inclusions

Shiyou shiyan dizhi
In recent years, shale gas exploration in the Cambrian Qiongzhusi Formation within the Deyang-Anyue rift trough of the Sichuan Basin has achieved significant breakthroughs, establishing it as a crucial succession area for unconventional hydrocarbon ...
Yanyou LI, Juan WU, Zhipeng ZHOU, Qianqian JIANG, Xuewen SHI, Yuran YANG, Chao LUO, Yifan HE, Heng WANG, Jingyi LIANG, Bin DENG   +10 more
doaj   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
Suna Lin, Linjie Li, JiJun Chen, Zhaokun Tao, Lifeng Zhang, Junqing Mao, Jinhu Wang   +6 more
wiley   +1 more source