Results 91 to 100 of about 1,022,309 (304)

Formation and evolution stages of gold rich Barika massive sulfide deposit, east of Sardasht, northern Sanandaj-Sirjan zone: based on structural, textural and fluid inclusion studies

open access: yesJournal of Economic Geology, 2010
Barika gold (and silver) rich massive sulfide deposit is located 18 km east of Sardasht, north western part of Sanandaj-Sirjan metamorphic zone. Rock units outcropped in this area are Cretaceous metamorphosed volcano-sedimentary rocks in green schist ...
Hossein Ali Tajeddin   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Ore genesis of the Chazangcuo Cu-Pb-Zn deposit in Tibet: evidence from mineralogy, fluid inclusions, S-Pb isotopes, and elemental geochemistry

open access: yesFrontiers in Earth Science
The Chazangcuo copper-lead-zinc deposit (hereafter referred to as the Chazangcuo deposit) is situated in the northern portion of the western section of the Gangdese polymetallic metallogenic belt in Tibet, with ore bodies strictly governed by Linzizong ...
Yan Li   +8 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Stable isotope studies on granulites from the high grade terrain of Southern India [PDF]

open access: yes
Fluid inclusion and petrologic characteristics of South India granulites and their bearing on the sources of metamorphic fluids are discussed. This paper served as a review and an introduction to the next paper by D. Jackson.
Harris, N. B. W.   +3 more
core   +1 more source

Effects of causality on the fluidity and viscous horizon of quark-gluon plasma

open access: yes, 2018
The second order Israel-Stewart-M$\ddot{u}$ller relativistic hydrodynamics has been applied to study the effects of causality on the acoustic oscillation in relativistic fluid.
Alam, Jan-e, Rahaman, Mahfuzur
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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