Results 111 to 120 of about 335,525 (308)
The Joftrud prospect area is located in the central Lut Block and 60 Km of Birjand city. The area comprises outcrops of pyroclastic (andesitic tuff), volcanic (hornblende andesite, pyroxene andesite, basaltic andesite), intrusive (diorite porphyry ...
Omid Shareipour +2 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Asimotrypes mesothermal gold deposit located in the Pangeon Mt (E. Macedonia, N. Greece), is part of the Western Rhodope Massif (WRM), which represents the metamorphic core complex of an alpine collision orogen. Alpine metamorphism, of U. Cretaceous -
Eliopoulos, Demetrios G.
core
Submarine magmatic–hydrothermal systems, where magmatic volatiles and fluids possibly serve as major sources of mineralization elements, have been extensively documented in numerous felsic‐hosted hydrothermal fields.
Xia Zhang +5 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Macroscopic calcite crystals are common in sedimenta¬ry strata, occurring both as tectonic veins and also filling one or more generations of septarian rupture or later brittle fractures in calcareous concretions.
Nelson, Campbell S., Pearson, Michael J.
core
Cathodoluminescence (CL) studies have previously shown that some secondary fluid inclusions in luminescent quartz are surrounded by dark, non-luminescent patches, resulting from fracture-sealing by late, trace-element-poor quartz. This finding has led to
Diamond, Larryn William +1 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
International audienceAn important aspect of quantitative fluid inclusion analysis using X-ray emission techniques concerns a knowledge of fluid inclusion depth and geometry to establish reliable absorption correction procedures. The aim of this study is
Philippot, Pascal +3 more
core +1 more source

