Results 101 to 110 of about 37,365 (307)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Magmatic and Metamorphic Fluids in Pegmatite Development: Evidence from Borujerd Complex, Iran [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2005
The Borujerd complex of western Iran is composed of intrusions and their surrounding contact aureole, with, pegmatites and quartz veins. Pegmatites differ in mineralogy, origin and age, and two groups can be distinguished. The Older Pegmatites (about 120
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Emeralds from the Delbegetey deposit (Kazakhstan): mineralogical characteristics and fluid-inclusion study

open access: yes, 2006
The aim of this study is to provide the first detailed mineralogical and fluid-inc1usion description of emeralds from the Delbegetey deposit (Kazakhstan).
Gavrilenko, Egor   +3 more
core   +1 more source

Phenolic compounds in oil-bearing fluid inclusions: Implications for water-washing and oil migration

open access: yes, 2018
In comparison to genetically related crude oils, oil-bearing fluid inclusions are often relatively enriched in polar compounds. Phenolic, carbazolic and benzocarbazolic compounds, which are part of the polar fraction, are characterised by elevated ...
Hallmann, C., George, S., Peters, C.
core   +1 more source

Ingredients for microbial life preserved in 3.5 billion-year-old fluid inclusions. [PDF]

open access: yesNat Commun, 2021
Mißbach H   +6 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Sources of the fluids for metasomatic magnesite of Ismakaevo deposit in the South Ural province (thermokryometry of fluid inclusions)

open access: yesЛитосфера, 2015
Bittern brine nature of fluid inclusions in magnesite of Ismakaevo deposits are confirmed not only by data of Cl-Br ion systematics, but also by methods of microthermometry.
M. T. Krupenin, A. A. Garaeva
doaj   +2 more sources

Home - About - Disclaimer - Privacy