Results 121 to 130 of about 112,724 (302)

Methane genesis within olivine-hosted fluid inclusions in dolomitic marble of the Hida Belt, Japan

open access: yesProgress in Earth and Planetary Science
Abiotic synthesis of hydrocarbon-bearing fluids during geological processes has a significant impact on the evolution of both the Earth's biosphere and the solid Earth.
Hironobu Harada, Tatsuki Tsujimori
doaj   +1 more source

Coarse-Grained Simulations of Membranes under Tension

open access: yes, 2010
We investigate the properties of membranes under tension by Monte-Carlo simulations of a generic coarse-grained model for lipid bilayers. We give a comprising overview of the behavior of several membrane characteristics, such as the area per lipid, the ...
Beate West   +7 more
core   +1 more source

Hydrocarbon Fluid Inclusion Fluorescence: A Review

open access: yes, 2009
Geological fluid inclusions are small voids that can contain a variety of liquids which are often found in natural minerals and rocks. Typically they are less than 10 micrometres in size that host fossil fluids which existed when the minerals grew or healed after fracture.
Blamey, Nigel J. F., Ryder, Alan G.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Brownian dynamics of elongated particles in a quasi-2D isotropic liquid

open access: yes, 2017
We demonstrate experimentally that the long-range hydrodynamic interactions in an incompressible quasi 2D isotropic fluid result in an anisotropic viscous drag acting on elongated particles.
Eremin, Alexey   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Averaging rheological quantities in descriptions of soft glassy materials

open access: yes, 2000
Many mean-field models have been introduced to describe the mechanical behavior of glassy materials. They often rely on averages performed over distributions of elements or states.
Armand Ajdari   +16 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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