Results 71 to 80 of about 30,517 (264)

Supercritical fluid in deep subduction zones as revealed by multiphase fluid inclusions in an ultrahigh-pressure metamorphic vein. [PDF]

Proc Natl Acad Sci U S A, 2023
Jin D, Xiao Y, Tan DB, Wang YY, Wang X, Li W, Su W, Li X.   +7 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Hydrocarbon Accumulation Periods in the Upper Paleozoic Strata of the Western Ordos Basin, China, Based on Fluid Inclusions and Basin Modeling. [PDF]

ACS Omega, 2023
Zhang F, Chen Z, Zhao Z, Gao J, Fu L, Li C, Zhang L.   +6 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Geological setting of silica in Dehnow-Abid region (Eshghabad northeast) using fluid inclusions studies

Journal of Economic Geology, 2017
Introduction Dehnow-Abid area is a part of the geological map of Eshghabad with scale 1:100000 (Aghanabati, 1994) that is located about 20 kilometers northeast of Eshghabad and in the coordinates of 57° 6´ 0" to 57° 10´ 0" eastern longitude and 34° 28 ...
Omid Yazdanpanah, Ali Akbar Hassannezhad
doaj   +1 more source

Characterization of Crude Oil, Formation Water, and Fluid Inclusions of Hydrocarbon-Bearing Strata and Their Hydrocarbon Geological Significance in the Wuliyasitai Southern Sub-sag of the Erlian Basin, China. [PDF]

ACS Omega, 2023
Si W, Hou D, Cao L.
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Magmatic and Metamorphic Fluids in Pegmatite Development: Evidence from Borujerd Complex, Iran [PDF]

Journal of Sciences, Islamic Republic of Iran, 2005
The Borujerd complex of western Iran is composed of intrusions and their surrounding contact aureole, with, pegmatites and quartz veins. Pegmatites differ in mineralogy, origin and age, and two groups can be distinguished. The Older Pegmatites (about 120
doaj  

Ingredients for microbial life preserved in 3.5 billion-year-old fluid inclusions. [PDF]

Nat Commun, 2021
Mißbach H, Duda JP, van den Kerkhof AM, Lüders V, Pack A, Reitner J, Thiel V.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source