Results 51 to 60 of about 220,158 (316)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Homotopy simulation of oscillatory powell–eyring nanofluid under rotating MHD Forces with Hall–ion slip and thermophoretic deposition

International Journal of Thermofluids
This paper presents an analytical investigation of the unsteady magneto hydrodynamic (MHD) flow of a Powell–Eyring nanofluid over an oscillating vertical plate in a rotating frame.
Fahad Sameer Alshammari, S. Karthik, P.K. Nagarajan, B.Vinoth Kumar, Nisha, Ali Akgül   +5 more
doaj   +1 more source

Fluid Structure Interaction (FSI) Simulation of the human eye under the air puff tonometry using Computational Fluid Dynamics (CFD) [PDF]

, 2018
The air puss test is a non-contact method used in different areas to investigate the material behaviour or the biomechanical properties of biological tissues such as skin, cornea, and soft tissue tumours and also to study fruit rmness or meat tenderness.
Maklad, O, Theofilis, V., Theofilis, V, Elsheikh, A, Maklad, Osama, Elsheikh, A.   +5 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Microscopic Computer Simulation of Fluids [PDF]

, 1997
When studying fluids it is frequently the case that the construction of a reasonable approximate theory becomes an elusive endeavor. The more difficult and interesting these problems are the better it is to have exact results, coming directly from the microscopic kinetics, both to test the existing theoretical approaches and to gain insights into new ...
P. Cordero, D. Risso
openaire   +1 more source

Deep Fluids: A Generative Network for Parameterized Fluid Simulations [PDF]

Computer Graphics Forum, 2019
AbstractThis paper presents a novel generative model to synthesize fluid simulations from a set of reduced parameters. A convolutional neural network is trained on a collection of discrete, parameterizable fluid simulation velocity fields. Due to the capability of deep learning architectures to learn representative features of the data, our generative ...
Byungsoo Kim 0001, Vinicius C. Azevedo, Nils Thuerey, Theodore Kim, Markus H. Gross, Barbara Solenthaler   +5 more
openaire   +4 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Estimation of 3D Permeability from Pore Network Models Constructed Using 2D Thin-Section Images in Sandstone Reservoirs

Energies, 2023
Using thin-section images to estimate core permeability is an economical and less time-consuming method for reservoir evaluation, which is a goal that many petroleum developers aspire to achieve.
Chengfei Luo, Huan Wan, Jinding Chen, Xiangsheng Huang, Shuheng Cui, Jungan Qin, Zhuoyu Yan, Dan Qiao, Zhiqiang Shi   +8 more
doaj   +1 more source

Numerical simulation of single droplet dynamics in three-phase flows using ISPH [PDF]

, 2013
In this study, a new surface tension formulation for modeling incompressible, immiscible three-phase fluid flows in the context of incompressible smoothed particle hydrodynamics (ISPH) in two dimensions has been proposed.
Yıldız, Mehmet, Yildiz, Mehmet, Tofighi, Nima   +2 more
core   +1 more source