Results 91 to 100 of about 111,384 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Fluidity of A713 Cast Alloy with and without Scrap Addition using Double Spiral Fluidity Test: A Comparison

open access: yes, 2012
Recycling of aluminum alloys often decrease fluidity, consequently influence the castability of the alloy. In this study, the fluidity of Al-Zn alloys, such as the standard A713 alloy with and without scrap addition has been investigated. The scrap added
D Benny Karunakar   +2 more
core   +1 more source

ON THE POSSIBLE FORMATION MECHANISM OF THE OPEN FRACTURING IN SEDIMENTARY BASINS

open access: yesГеодинамика и тектонофизика
The paper shows that the formation of orthogonal systems of open macrofractures (cleavages) of sedimentary basins can occur at the stage of diagenesis during the first hundreds of years for a small range of shelf depths (up to 100 m) during sedimentation.
Yu. L. Rebetsky
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Memory and music in Mikhail Bulgakov's The Master and Margarita: Defying the regime [PDF]

open access: yesLogos et Littera: Interdisciplinary Approaches to Text, 2017
Mikhail Bulgakov’s The Master and Margarita reveals intricate intersections, which are negotiated via memory and writing. Witnessing the collapse of the Russian Empire and the emergence of the Soviet Union, Bulgakov devises multiple ways to engage not ...
Nataliya Shpylova-Saeed   +1 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Fluidity of aluminum alloys and magnesium alloys [PDF]

open access: yes, 1983
publisherInvestigations for the fluidity of aluminum alloys and magnesium alloys were carried out by means of spiral-fluidity shell mould at superheated temperatures of 50, 100, 150 and 200℃.
佃, 誠, 友本, 清一, 鎌土, 重晴
core  

Fluidity and Education

open access: yes, 2019
This article shows why and how fluidity educates and is therefore of educational relevance for student teachers. If education sees the developmental process of the whole person, with regard to his or her “humanity”, as a life-long learning process, in ...
Manfred Oberlechner
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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